Results 91 to 100 of about 10,459,346 (392)
, 2008 Governments and international organizations worry increasingly about systemic risk, under which the world’s financial system can collapse like a row of dominoes.
Schwarcz, Steven L.
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Default risk in an interconnected banking system with endogeneous asset markets : [Version: August 2011] [PDF]
, 2011 This paper analyzes the emergence of systemic risk in a network model of interconnected bank balance sheets. Given a shock to asset values of one or several banks, systemic risk in the form of multiple bank defaults depends on the strength of balance ...
Bluhm, Marcel, Krahnen, Jan Pieter
core
Regulating Systemic Risk: Towards an Analytical Framework [PDF]
, 2003 The global financial crisis demonstrated the inability and unwillingness of financial market participants to safeguard the stability of the financial system.
Steven L. Schwarcz +9 more
core +3 more sources
Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma
Molecular Oncology, EarlyView.PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga +2 more
wiley +1 more source
Backtesting Marginal Expected Shortfall and Related Systemic Risk Measures
Management Sciences, 2019 This paper proposes an original approach for backtesting systemic risk measures. This backtesting approach makes it possible to assess the systemic risk measure forecasts used to identify the financial institutions that contribute the most to the overall
Denisa Banulescu-Radu +3 more
semanticscholar +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Earth's FutureRecently, unprecedented compound drought and heatwave (CDHW) events have severely damaged terrestrial ecosystems, but their dynamics, formation mechanisms, and threats are still insufficiently understood. Here, using simulations from nine‐member ensemble
Bohao Li +7 more
doaj +1 more source
Systemic risk across sectors; Are banks different? [PDF]
This research compares systemic risk in the banking sector, the insurance sector, the construction sector, and the food sector. To measure systemic risk, we use extreme negative returns in stock market data for a time-varying panel of the 20 largest U.S.
Michiel Bijlsma, Sander Muns
core
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source