Results 91 to 100 of about 9,640,886 (365)

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Analysis of pork price fluctuations during the special era when African swine fever and COVID-19 epidemic coexisted: an empirical study in Macau, China

Frontiers in Sustainable Food Systems
IntroductionEmergent crises can have a catastrophic impact on regional economic systems. The concurrent outbreaks of African Swine Fever (ASF) and the COVID-19 pandemic have severely affected Macau’s pork industry, making it an interesting case study for
Fang Xu, Fang Xu, Xiaoyong Ni, Xiaoyong Ni, Kai Liu, Kai Liu, Ming Wang, Ming Wang, Kangye Tan, Jun Hu, Jun Hu   +10 more
doaj   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

The Renminbi and Systemic Risk [PDF]

Journal of International Economic Law, 2017
The internationalization of China’s currency, the renminbi (“RMB”), is arising in ways that depart considerably from historical precedent and what “law and macroeconomic” theory would predict. Instead of waiting for international markets for its currency to evolve organically, the Chinese government has undertaken a quasi-mercantilist strategy designed
Chris Brummer, Chris Brummer
openaire   +3 more sources

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Default risk in an interconnected banking system with endogeneous asset markets : [Version: August 2011] [PDF]

, 2011
This paper analyzes the emergence of systemic risk in a network model of interconnected bank balance sheets. Given a shock to asset values of one or several banks, systemic risk in the form of multiple bank defaults depends on the strength of balance ...
Bluhm, Marcel, Krahnen, Jan Pieter
core  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

The five investor camps that try to beat the stock market

Borsa Istanbul Review, 2020
This paper categorizes investors into five groups. They are: efficient markets, risk premium, genius superior traders, rejectors of efficient market theory and those who use research to make superior risk adjusted returns.
William T. Ziemba
doaj  

Fund Management and Systemic Risk - Lessons from the Global Financial Crisis [PDF]

, 2013
Fund managers play an important role in increasing efficiency and stability in financial markets. But research also indicates that fund management in certain circumstances may contribute to the buildup of systemic risk and severity of financial crises ...
Allen, Andersen, Aragon, Baba, BCBS, Bengtsson, Bengtsson, Bernanke, Bikhchandani, BIS, Borio, Borio, Brunnermeier, Buttonwood, CESR, Chan-Lau, Christoffersen, Cobley, Cole, Crane Data Archives, Crouchy, CSSF, Davis, Davis, Davis, Delbecque, Diamond, Dierick, Duffie, Duffie, Duygan-Bump, Dwyer, Edwards, Elsas, European Commission, European Parliament and Council of the European Union, Fender, Financial Stability Oversight Council, FSB, Garbaravicius, Gorton, Greene, Gunnarsdottir, IMF, Kahan, Kessler, Kiff, Kindleberger, King, Klapper, Kroszner, Lelyveld, Lescrauwaet, Lipper, Lyon, Martin, McCabe, Mezzacapo, Miles, Minsky, O'Kane, OECD, Olson, Pennacchi, Persaud, Rajan, Rochet, Rule, Santomero, Schich, Schmidt, Schultes, Shleifer, Standard & Poor's, Stecklow, Stigum, Vause, Wagner, Wiethuechter   +78 more
core   +2 more sources

Systemic Risk Assessment in Complex Supply Networks

IEEE Systems Journal, 2018
The growth in size and complexity of supply chains has led to compounded risk exposure, which is hard to measure with existing risk management approaches.
Anna Ledwoch, A. Brintrup, J. Mehnen, A. Tiwari   +3 more
semanticscholar   +1 more source