Assessing the Role of Volumetric Brain Information in Multiple Sclerosis Progression [PDF]
Multiple sclerosis is a chronic autoimmune disease that affects the central nervous system. Understanding multiple sclerosis progression and identifying the implicated brain structures is crucial for personalized treatment decisions. Deformation-based morphometry utilizes anatomical magnetic resonance imaging to quantitatively assess volumetric brain ...
arxiv
Lung function and the response to exercise in systemic sclerosis [PDF]
S. Godfrey+2 more
openalex +1 more source
Current advances in the treatment of systemic sclerosis.
H. Bukiri, E. Volkmann
semanticscholar +1 more source
Gastrointestinal Manifestations of Systemic Sclerosis
Systemic sclerosis (SSc) is a rare autoimmune disease characterized by fibroproliferative alterations of the microvasculature leading to fibrosis and loss of function of the skin and internal organs.
Isabel M. McFarlane+13 more
semanticscholar +1 more source
Interpretability of Uncertainty: Exploring Cortical Lesion Segmentation in Multiple Sclerosis [PDF]
Uncertainty quantification (UQ) has become critical for evaluating the reliability of artificial intelligence systems, especially in medical image segmentation. This study addresses the interpretability of instance-wise uncertainty values in deep learning models for focal lesion segmentation in magnetic resonance imaging, specifically cortical lesion ...
arxiv +1 more source
Diffuse Systemic Sclerosis Presenting as Infarction of Colon [PDF]
David Edwards+3 more
openalex +1 more source
Platelet microparticles sustain autophagy-associated activation of neutrophils in systemic sclerosis
Platelet microparticles from patients with systemic sclerosis prompt endothelial cell activation, neutrophil recruitment, and lung fibrosis. Platelets nurture neutrophil damage Systemic sclerosis, or scleroderma, is a complicated inflammatory fibrotic ...
N. Maugeri+12 more
semanticscholar +1 more source
A reaction-diffusion model for relapsing-remitting multiple sclerosis with a treatment term [PDF]
We present a mathematical study for the development of multiple sclerosis based on a reaction-diffusion system. The model describes interactions among different populations of human cells, motion of immune cells stimulated by cytokines, consumption of myelin sheath due to anomalously activated lymphocytes and its restoration by oligodendrocytes ...
arxiv
Cardiorespiratory performance in systemic sclerosis. [PDF]
S. Godfrey+2 more
openalex +1 more source
The immunopathogenesis of fibrosis in systemic sclerosis
Systemic sclerosis (SSc) is an idiopathic systemic autoimmune disease. It is characterized by a triad of hallmarks: immune dysfunction, fibrosis and vasculopathy.
Melvyn Brown, Steven O’Reilly
semanticscholar +1 more source