Results 91 to 100 of about 293,399 (308)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller +14 more
wiley +1 more source
Widespread mutagenesis and chromosomal instability shape somatic genomes in systemic sclerosis
Nature CommunicationsSystemic sclerosis is a connective tissue disorder characterized by excessive fibrosis that primarily affects women, and can present as a multisystem pathology.
Sriram Vijayraghavan +7 more
doaj +1 more source
Systemic Sclerosis in Males—Deciphering the Enigma of Erasmus Syndrome
Indian Journal of DermatologyBackground: Systemic sclerosis is an autoimmune connective tissue disease characterized by fibrosis in skin and internal organs. Chronic exposure to silica may not only lead to silicosis of lungs but also systemic sclerosis.
Reena K. Sharma, Mudita Gupta
doaj +1 more source
Bosentan for digital ulcers prevention does not worsen cardiopulmonary exercise test parameters in SSc patients with interstitial lung disease [PDF]
, 2016 Bosentan for digital ulcers prevention does not worsen cardiopulmonary exercise test parameters in SSc patients with interstitial lung ...
Amoroso, Daria +7 more
core +1 more source
Immunogenetics of Systemic Sclerosis
GenesSystemic sclerosis (SSc) is a rare autoimmune connective tissue disorder characterized by massive fibrosis, vascular damage, and immune imbalance. Advances in rheumatology and immunology over the past two decades have led to a redefinition of systemic sclerosis, shifting from its initial perception as primarily a “hyperfibrotic” state towards a ...
Olga Gumkowska-Sroka +2 more
openaire +3 more sources
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Adie’s Tonic Pupil in Systemic Sclerosis: A Rare Association
Case Reports in Ophthalmological Medicine, 2015 We report a rare association of Adie’s tonic pupil in a patient with systemic sclerosis who was otherwise systemically stable. This paper is an effort to unravel whether the tonic pupil and systemic sclerosis are an association by chance (which may be ...
Anusha Venkataraman +2 more
doaj +1 more source
Do we need broad immunological work-up in all patients with CIS? [PDF]
, 2012 BACKGROUND: The aim of this study was to determine the prevalence of altered immunological tests and their clinical significance in patients with clinically isolated syndrome (CIS) suggestive of multiple sclerosis (MS). ----- PATIENTS AND METHODS:
Adamec, Ivan +6 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe +7 more
wiley +1 more source
Annals of Occupational and Environmental Medicine, 2017 Background Occupational exposure to crystalline silica is a potential risk factor for various systemic autoimmune diseases including systemic sclerosis.
Jae Yoon Kim +7 more
doaj +1 more source