Results 101 to 110 of about 311,988 (356)

Heterogeneity of Rheumatoid Arthritis–Associated Interstitial Lung Disease by Longitudinal Forced Vital Capacity Trajectory and Associations With Disease Outcomes

Arthritis Care &Research, EarlyView.
Objective We aimed to identify unique disease trajectories within rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) based on longitudinal forced vital capacity (FVC) values and their associated clinical outcomes. Methods We performed a cohort study of RA‐ILD within the Veterans Health Administration from 1999 to 2021.
Bryant R. England, Yangyuna Yang, Punyasha Roul, Tate M. Johnson, Scott M. Matson, Grant W. Cannon, Brian C. Sauer, Jeffrey R. Curtis, Joshua F. Baker, Ted R. Mikuls   +9 more
wiley   +1 more source

Systemic sclerosis due to crystalline silica exposure among jewelry workers in Korea: two case reports

Annals of Occupational and Environmental Medicine, 2017
Background Occupational exposure to crystalline silica is a potential risk factor for various systemic autoimmune diseases including systemic sclerosis.
Jae Yoon Kim, Sang Yoon Do, Young Hoon Moon, Chul Gab Lee, Yun Sung Kim, Byung Soon Choi, Eun-A Kim, Han Soo Song   +7 more
doaj   +1 more source

Autologous Hematopoietic Stem Cell Therapy of the Subjects with Systemic Sclerosis: Electromyographic Results of the Masticatory Muscles

Prague Medical Report, 2020
Musculoskeletal system impairment is a major cause of functional alterations in subjects with systemic sclerosis. Autologous hematopoietic stem cell therapy (AHSCT) may have an important role in the treatment functional of systemic sclerosis patients ...
Thamyres Branco, Ligia Franco Oliveira, Marcelo Palinkas, Paulo Batista de Vasconcelos, Maria Carolina Oliveira, Belinda Pinto Simões, Isabela Hallak Regalo, Selma Siéssere, Simone Cecilio Hallak Regalo   +8 more
doaj   +1 more source

Systemic Acrolein Elevations in Mice With Experimental Autoimmune Encephalomyelitis and Patients With Multiple Sclerosis [PDF]

, 2018
Demyelination and axonal injury are the key pathological processes in multiple sclerosis (MS), driven by inflammation and oxidative stress. Acrolein, a byproduct and instigator of oxidative stress, has been demonstrated as a neurotoxin in experimental ...
Acosta, Glen, Hayward, Lee, Mattson, David, Race, Nicholas, Shi, Riyi, Tang, Jonathan, Tian, Ran, Tully, Melissa, Zheng, Lingxing   +8 more
core   +1 more source

Systemic Sclerosis

Medicine, 2010
We designed the current study to describe the spectrum of disease expression in systemic sclerosis (SSc) in a large cohort and to develop diagnostic criteria for SSc. We assessed patients in the Canadian Scleroderma Research Group Registry by standardized history, physical examination, and laboratory testing.
Marie, Hudson, Marvin J, Fritzler, Murray, Baron   +2 more
openaire   +2 more sources

Serum Soluble Mediator Signatures of Lupus Nephritis: Histologic Features and Response to Treatment

Arthritis Care &Research, EarlyView.
Objective Lupus nephritis (LN) management remains challenging, and novel noninvasive biomarkers are needed. This study quantified serum soluble mediators in the Accelerating Medicines Partnership (AMP) LN cohort to identify biomarkers of histologic features and treatment response.
Andrea Fava, Catriona A. Wagner, Carla J. Guthridge, Susan Macwana, Wade DeJager, Melissa E. Munroe, Peter Izmirly, H. Michael Belmont, Betty Diamond, Anne Davidson, Paul J. Utz, Michael H. Weisman, Philip M. Carlucci, Maria Dall'Era, Kenneth Kalunian, Chaim Putterman, Jennifer Anolik, Jennifer L. Barnas, David Wofsy, Diane Kamen, Richard A. Furie, Deepak A. Rao, the Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus Network, Chun‐Hao Lee, Derek Fine, Manny Monroy‐Trujillo, Ummara Shah, Mariko Ishimori, Robert M. Clancy, Michael Belmont, Ming Wu, Nicole Bornkamp, Evan Der, Beatrice Goilav, Nicole Jordan, Daniel Schwartz, James Pullman, David Wofsy, Dawn Smilek, Patti Tosta, Matthias Kretzler, Celine C. Berthier, E. Steve Woodle, Dave Hildeman, Michael Brenner, Michelle Petri, Joel M. Guthridge, Jill Buyon, Judith A. James   +48 more
wiley   +1 more source

Assessment of Skin in Patients With Systemic Sclerosis Using High‐Frequency Ultrasound and Shear Wave Elastography: A Comparative Study With Histology, Molecular, and Clinical Parameters

Arthritis Care &Research, EarlyView.
Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histologic markers of skin fibrosis has not been reported. We evaluated US‐based skin assessments for their face validity (differentiation between involved SSc and healthy
Ruhani Desai, Filemon Tan, Minghua Wu, Jeffery L. Browning, Samuel Theodore, Meng Zhang, Brian Skaug, Harshdeep Singh Chawla, Manmohan Singh, Salavat Aglyamov, Kirill V. Larin, Maureen Mayes, Shervin Assassi   +12 more
wiley   +1 more source

Serum VEGF levels are related to the presence of pulmonary arterial hypertension in systemic sclerosis

BMC Pulmonary Medicine, 2009
Background The association between systemic sclerosis and pulmonary arterial hypertension (PAH) is well recognized. Vascular endothelial growth factor (VEGF) has been reported to play an important role in pulmonary hypertension.
Sakkas Lazaros, Koutroumpas Athanasios, Ziogas Athanasios, Koutsokera Angela, Kiropoulos Theodoros, Kostikas Konstantinos, Zakynthinos Epaminondas, Papaioannou Andriana I, Gourgoulianis Konstantinos I, Daniil Zoe D   +9 more
doaj   +1 more source

Single-cell transcriptome analysis identifies skin-specific T-cell responses in systemic sclerosis

, 2021
Alyxzandria M. Gaydosik, Tracy Tabib, Robyn T. Domsic, Dinesh Khanna, Robert Lafyatis, Patrizia Fuschiotti   +5 more
openalex   +2 more sources

Copeptin as a Biomarker of Microcirculation Alterations in Systemic Sclerosis

Clinical, Cosmetic and Investigational Dermatology, 2023
Magdalena Maciejewska,1 Albert Stec,2 Michał Zaremba,2 Cezary Maciejewski,3 Lidia Rudnicka,2 Mariusz Sikora4 1Department of Dermatology, Doctoral School of Medical University of Warsaw, Warsaw, Poland; 2Department of Dermatology, Medical ...
Maciejewska M, Stec A, Zaremba M, Maciejewski C, Rudnicka L, Sikora M   +5 more
doaj