Results 101 to 110 of about 1,628,316 (351)
Genetics of scleroderma: implications for personalized medicine?
BMC Medicine, 2013 Significant advances have been made in understanding the genetic basis of systemic sclerosis (scleroderma) in recent years. Can these discoveries lead to individualized monitoring and treatment?
Assassi Shervin +3 more
doaj +1 more source
Tracking Impact of Interstitial Lung Disease in Systemic Sclerosis in a Complete Nationwide Cohort.
American Journal of Respiratory and Critical Care Medicine, 2019 RATIONALE Interstitial lung disease (ILD) represents a major challenge in systemic sclerosis (SSc), but there are no precise, population-based data on its overall impact, limiting opportunities for screening and management strategies.
A. Hoffmann-Vold +12 more
semanticscholar +1 more source
Advanced Science, EarlyView.In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han +10 more
wiley +1 more source
The role of allograft inflammatory factor 1 in systemic sclerosis [PDF]
, 2006 Purpose of review: The aim of this article is to review studies which support the hypothesis that allograft inflammatory factor-1, a protein initially identified in chronically rejected cardiac allografts, may be involved in the pathogenesis of the ...
Artlett, Carol M. +2 more
core +2 more sources
Case Reports in Immunology, 2017 Systemic sclerosis, or scleroderma, is a complex medical disorder characterized by limited or diffuse skin thickening with frequent involvement of internal organs such as lungs, gastrointestinal tract, or kidneys.
Bumsoo Park +4 more
doaj +1 more source
Advanced Science, EarlyView.This study presents a novel portable grasp‐assist glove, weighing only 47 g. The glove integrates smart adhesive pads and a hands‐free control interface based on IMU, designed to aid rheumatic patients with impaired hand function. The system enables switchable adhesion with independent control and detection of user release intent.
Shiqiang Wang +11 more
wiley +1 more source
Endothelial to mesenchymal transition (EndoMT) in the pathogenesis of Systemic Sclerosis-associated pulmonary fibrosis and pulmonary arterial hypertension. Myth or reality? [PDF]
, 2016 Systemic Sclerosis (SSc) is a systemic autoimmune disease characterized by progressive fibrosis of skin and multiple internal organs and severe functional and structural microvascular alterations.
Jimenez, Sergio A. +1 more
core +2 more sources
Listerin Alleviates Alzheimer's Disease through IRE1‐mediated Decay of TLR4 mRNA
Advanced Science, EarlyView.Alzheimer's disease (AD) progression is influenced by microglia‐mediated neuroinflammation. Here, it is demonstrated that Listerin suppresses neuroinflammatory signaling and cognitive impairment in AD models by triggering IRE1α‐mediated TLR4 mRNA decay. Adenoviral Listerin delivery reduces amyloid‐β pathology, positioning it as a new therapeutic target.
Fei Qin +9 more
wiley +1 more source
Audio-vestibular symptoms in systemic autoimmune diseases [PDF]
, 2018 Immune-mediated inner ear disease can be primary, when the autoimmune response is against the inner ear, or secondary. The latter is characterized by the involvement of the ear in the presence of systemic autoimmune conditions. Sensorineural hearing loss
Adelchi, Croce +7 more
core +1 more source
Advanced Science, EarlyView.This review explores the cutting‐edge development of bio‐integrated flexible electronics for real‐time hemodynamic monitoring in cardiovascular healthcare. It covers key physiological indicators, innovative sensing mechanisms, and materials considerations. This paper highlights the application of both invasive and non‐invasive devices in cardiovascular
Ke Huang, Zhiqiang Ma, Bee Luan Khoo
wiley +1 more source