Results 251 to 260 of about 311,988 (356)

Distinct effects of complement C4A and C4B copy number in Systemic Sclerosis serological and clinical subtypes

Arthritis &Rheumatology, Accepted Article.
Objective Complement component 4 (C4), encoded by C4A and C4B within the major histocompatibility complex (MHC) on chromosome 6, regulates the immune response and clears immune complexes. Variable copy number (CN) of C4 genes and retroviral HERV‐K element influence its function.
Javier Martínez‐López, Carlos Rangel‐Peláez, Inmaculada Rodriguez‐Martin, Alfredo Guillen‐Del‐Castillo, Carmen P Simeón‐Aznar, José L Callejas, International SSc Group; PRECISESADs Clinical Consortium, Oliver Distler, Susanna M Proudman, Mandana Nikpour, Australian Scleroderma Interest Group (ASIG), Nicolas Hunzelmann, Gianluca Moroncini, Jeska K de Vries‐Bouwstra, Ariane L Herrick, Yannick Allanore, Marta E. Alarcon‐Riquelme, Lorenzo Beretta, Shervin Assassi, Christopher P Denton, Maureen D Mayes, Javier Martin, Marialbert Acosta‐Herrera, Martin Kerick   +23 more
wiley   +1 more source

Systemic Sclerosis in Kazakh Patients: A Preliminary Case-Control Immunogenetic Profiling Study. [PDF]

Pathophysiology
Zaripova L, Baigenzhin A, Boltanova A, Zhabakova Z, Solomadin M, Kozina L.   +5 more
europepmc   +1 more source

Pulmonary Hypertension Associated with Systemic Sclerosis (Review)

H.V. Mostbauer
openalex   +1 more source

Linezolid prevents fibroblast activation and ameliorates tissue fibrosis by inhibition of mitochondrial translation

Arthritis &Rheumatology, Accepted Article.
Background Beyond its role as a ribosome‐targeting antibiotic, linezolid was recently shown to modulate immune responses by inhibiting mitochondrial translation. Since mitochondrial dysfunction is implicated in various fibrotic diseases, including systemic sclerosis (SSc), this study aimed to evaluate the antifibrotic potential of linezolid and ...
Xuezhi Hong, Yanhua Xiao, Haodong Qi, Shihao Zhu, Tim Filla, Andrea‐Hermina Györfi, Yi‐Nan Li, Meilin Xu, Langxian Zhi, Thuong Trinh‐Minh, Clara Dees, Georg Schett, Jörg H.W. Distler, Alexandru‐Emil Matei   +13 more
wiley   +1 more source

Eradication of Small Intestinal Bacterial Overgrowth in Systemic Sclerosis: Current Treatment and Perspectives-A Narrative Review. [PDF]

Biomedicines
Radić M, Belančić A, Vučković M, Fajkić A, Rogoznica Pavlović M, Radić J.   +5 more
europepmc   +1 more source

Increased incidence of tuberculosis in patients of systemic sclerosis on dexamethasone pulse therapy: A short communication from Kashmir

, 2008
Ahmad Qazi, Shah Iffat, Nauman Qazi, Sameem Farah, Sultan Javaid   +4 more
openalex   +1 more source

Drugs induced Raynaud's phenomenon and underlying mechanism: a disproportionality analysis from the WHO pharmacovigilance database

Arthritis &Rheumatology, Accepted Article.
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's Phenomenon (RP) and to explore their potential pathophysiological mechanisms through a mixed disproportionality/clustering analysis from the WHO pharmacovigilance database.
Alex Hlavaty, Loubna Dari, Jean‐Luc Cracowski, Matthieu Roustit, Charles Khouri   +4 more
wiley   +1 more source

Systemic sclerosis complicated by skin ulcers: A case report and literature review. [PDF]

J Int Med Res
Lu R, Wang H, Zhang L, Wu J, Liu J.
europepmc   +1 more source

Exposure to occupational inhalants and the risk of developing rheumatoid arthritis: A systematic review and meta‐analysis

Arthritis &Rheumatology, Accepted Article.
Objective: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint pain, swelling, and stiffness. While smoking is a well‐established risk factor for RA, the role of occupational inhalants in RA development is less well recognized.
Qianwen Liu, Xin Song, Emily Mauro, Yuan Jiang, Klementy Shchetynsky, PLars Klareskog, Lars Alfredsson, Xia Jiang   +7 more
wiley   +1 more source

Reply: Macrophage Activation in Systemic Sclerosis. [PDF]

JACC Basic Transl Sci
Jones XM, Soussi S, Bottini N, Ibrahim AGE, Marbán E.   +4 more
europepmc   +1 more source