Results 101 to 110 of about 49,176,657 (311)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Background Globally, research and policy groups often lack the expertise to develop models to analyze invasive and native species of agroecological and veterinary/human health importance; models to inform management and policy under extant and climate ...
Andrew Paul Gutierrez +6 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Sectoral investments to achieve water, energy and land SDG under climate change uncertainty
Achieving the sustainable development goals (SDGs) requires a deep understanding of the intricate relationships between water, energy, food, and land resources, particularly in the context of a growing global population and climate change.
Adriano Vinca +4 more
doaj +1 more source
Social Intelligence Mining: Transforming Land Management with Data and Deep Learning
The integration of social intelligence mining with Large Language Models (LLMs) and unstructured social data can enhance land management by incorporating human behavior, social trends, and collective decision-making.
Mohammad Reza Yeganegi +2 more
doaj +1 more source
The aim of this thesis is to conduct a general investigation in the field of sparse matrices, to investigate and compare various techniques for handling sparse systems suggested in the literature, to develop some new techniques, and to discuss the feasibility of using sparsity techniques in the solution of overdetermined equations and the eigenvalue ...
openaire +2 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
A system for transformational analysis [PDF]
A system is proposed here for assigning a derived P-marker to a given transformed sentence and obtaining the corresponding base P-marker at the same time. Rules of analytical phrase-structure grammar for such a system have associated with them information pertaining to the transformational histories of their own derivation.
openaire +2 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source

