Results 101 to 110 of about 34,801,835 (296)
Social Intelligence Mining: Transforming Land Management with Data and Deep Learning
LandThe integration of social intelligence mining with Large Language Models (LLMs) and unstructured social data can enhance land management by incorporating human behavior, social trends, and collective decision-making.
Mohammad Reza Yeganegi +2 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Environmental Sciences EuropeBackground Globally, research and policy groups often lack the expertise to develop models to analyze invasive and native species of agroecological and veterinary/human health importance; models to inform management and policy under extant and climate ...
Andrew Paul Gutierrez +6 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Sectoral investments to achieve water, energy and land SDG under climate change uncertainty
Environmental Research: Infrastructure and SustainabilityAchieving the sustainable development goals (SDGs) requires a deep understanding of the intricate relationships between water, energy, food, and land resources, particularly in the context of a growing global population and climate change.
Adriano Vinca +4 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Ecological determinants of Cope’s rule and its inverse
Communications BiologyCope’s rule posits that evolution gradually increases the body size in lineages. Over the last decades, two schools of thought have fueled a debate on the applicability of Cope’s rule by reporting empirical evidence, respectively, for and against Cope’s ...
Shovonlal Roy +2 more
doaj +1 more source
Systems Theoretic Process Analysis
, 2016 Thesis: S.M. in Engineering Systems, Massachusetts Institute of Technology, School of Engineering, Institute for Data, Systems, and Society, 2016.Cataloged from PDF version of thesis.Includes bibliographical references (pages 79-82).The automotive ...
Suo, Dajiang
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source