Results 111 to 120 of about 13,108,811 (339)

Social Intelligence Mining: Transforming Land Management with Data and Deep Learning

open access: yesLand
The integration of social intelligence mining with Large Language Models (LLMs) and unstructured social data can enhance land management by incorporating human behavior, social trends, and collective decision-making.
Mohammad Reza Yeganegi   +2 more
doaj   +1 more source

Radar altimetry systems cost analysis [PDF]

open access: yes
This report discusses the application and cost of two types of altimeter systems (spaceborne (satellite and shuttle) and airborne) to twelve user requirements.
Denman, W. F., Escoe, D., Heuring, F. T.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Sediment transport pathways and organic carbon burial impacted by offshore wind farms in shelf seas

open access: yesCommunications Earth & Environment
The rapid expansion of offshore wind farms increasingly impacts ocean environments. Little is known concerning synergistic effects of wind farms on large-scale sediment transport and seabed ecosystem functioning.
Jiayue Chen   +6 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Analysis of data processing systems [PDF]

open access: yes
Mathematical simulation models and software monitoring of multiprogramming computer ...
Crooke, S., Minker, J., Yeh, J.
core   +1 more source

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