Results 181 to 190 of about 13,108,811 (339)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Suicide in Bangladesh: An Ecological Systems Analysis. [PDF]

Brain Behav
Arafat SMY, Saleem T.
europepmc   +1 more source

Racial & ethnic disparities in geographic access to critical care in the United States: A geographic information systems analysis. [PDF]

PLoS One, 2023
Burdick KJ, Rees CA, Lee LK, Monuteaux MC, Mannix R, Mills D, Hirsh MP, Fleegler EW.   +7 more
europepmc   +1 more source

Predicting Sorption of Diverse Organic Compounds in Soil-Water Systems: Meta-Analysis, Machine Learning Modeling, and Global Soil Mapping

Jiachun Sun, Kai Zhang, Huichun Zhang
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A dynamical systems analysis of criminal behavior using national longitudinal survey of youth data. [PDF]

PLoS One
McMillon D, Morenoff J, Simon C, Lane E.
europepmc   +1 more source

Erratum for “Transforming the Acquisition Enterprise: A Framework for Analysis and a Case Study of Ship Acquisition”, Systems Engineering , Vol. 10, No. 2, 2007 [PDF]

, 2014
Michael J. Pennock
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Systems analysis of clinical incidents: development of a new edition of the London Protocol. [PDF]

BMJ Qual Saf
Vincent C, Irving D, Bellandi T, Higham H, Michel P, Staines A, Adams S, Brown J, Hibbert PD, Hemmelgarn C, Joseph L, Pires K, Sheridan S, Sunol R, Ushiro S, Wu AW, Zambon L.   +16 more
europepmc   +1 more source

Socioecological systems analysis of potential factors for cholera outbreaks and assessment of health system's readiness to detect and respond in Ilemela and Nkasi districts, Tanzania. [PDF]

BMC Health Serv Res, 2023
Ngingo BL, Mchome ZS, Bwana VM, Chengula A, Mwanyika G, Mremi I, Sindato C, Mboera LEG.   +7 more
europepmc   +1 more source