Results 111 to 120 of about 740,666 (264)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

A multi-source heterogeneous data fusion method for intelligent systems in the Internet of Things

Intelligent Systems with Applications
The advent of the Internet of Things (IoT) has revolutionized the field of intelligent system development by providing an extensive amount of data from IoT devices, essential for the management of these systems and the creation of innovative services ...
Rongrong Sun, Yuemei Ren
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Examining the decision criteria on BIM-LCA: A case study

Construction Economics and Building
The mainstay of the extant literature on BIM-LCA has concentrated on comparing two materials for building elements and selecting the most environmentally friendly option based on the quantitative results from the LCA analysis.
Gerardo Sistos-Sescosse, Bernard Tuffour Atuahene, Oluwadunsin Ajulo, Ishmael Adams   +3 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

TECHNIQUE OF IMPROVEMENT OF BUSINESS-PROCESSES AT INFORMATION SYSTEMS DESIGNING ON EXAMPLE OF SOTT OPEN SOCIETY "ROSNEFT-KRASNODARNEFTEGAZ"

Advanced Engineering Research, 2006
The brief characteristic and a technique of realization of the analysis and improvement of administrative and industrial business business-processes are given in the article.
V.P. MIRONYUK, N.G. SHAMRAYEV
doaj  

Patient safety in the operating theatre: An ongoing endeavour

Proceedings of Singapore Healthcare
Background Patient safety is of paramount importance in healthcare delivery. This is especially so in the high-risk and complex environment of the operating theatre. Objectives The purpose of this narrative review is to illustrate the risks that patients
David Chee, Tong Khee Tan
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Analysis and improvement of a publication System : New approaches on Web Applications

, 2008
The aim of this thesis is the research in modern web development tools to demonstrate in which ways can this raised technologies help to make a real application more user friendly, easy to maintain and extend, and more reliable. Some new approaches to Web applications will be presented in comparison with the traditional way, and a real application will
openaire   +1 more source