Results 101 to 110 of about 12,579,596 (265)
Final report of the GARNet Advisory Committee on Arabidopsis Systems Biology in the UK, June 2006. [PDF]
, 2006 Biological research using Arabidopsis thaliana is adopting systems approaches in some areas. Arabidopsis researchers must build the capacity for systems analysis, if the UK’s strength in Arabidopsis biology is to be reflected in sub-systems models that ...
?, ?, Millar, Andrew; id_orcid
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Aspergilli: Systems biology and industrial applications
, 2012 Aspergilli are widely used as cell factories for the production of food ingredients, enzymes and antibiotics. Traditionally, improvement of these cell factories has been done using classical methods, that is, random mutagenesis and screening; however ...
Christoph Knuf +7 more
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
, 2017 Mathematical modeling has emerged as a powerful descriptive and predictive tool to analyze complex biological systems. It is deeply embedded in the systems biology cycle, providing the means to deliver predictive quantitative models.
Cvijovic, Marija, +2 more
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
From Systems Biology to Systems Biomedicine
, 2012 peer reviewedSystems Biology is about combining theory, technology, and targeted experiments in a way that drives not only data accumulation but knowledge as well.
Paul MA Antony +5 more
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FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
6th Annual Systems Biology Symposium: Systems Biology and the Environment
, 2007 Systems biology recognizes the complex multi-scale organization of biological systems, from molecules to ecosystems. The International Symposium on Systems Biology is an annual two-day event gathering the most influential researchers transforming biology
Galitski, Timothy, P.
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Systems biology in toxicology and environmental health
, 2015 Systems Biology in Environmental Health: From the Genome to the Epigenome brings a systems biological perspective to recent findings that link environmental exposures to human disease.
Fry, Rebecca C.
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