Results 81 to 90 of about 11,342,017 (299)
Information and Computation, 2014 Hybrid Systems are dynamical systems presenting both discrete and continuous evolution. Hybrid Automata are a formal model for hybrid systems, originally proposed to study embedded systems, where a discrete control acts on a continuously changing environment.
Ezio Bartocci +2 more
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Systems biology : philosophical foundations /
, 2007 Systems biology is a vigorous and expanding discipline, in many ways a successor to genomics and perhaps unprecedented in its combination of biology with a great many other sciences, from physics to ecology, from mathematics to medicine, and from ...
Boogerd, Fred C.
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Computational challenges of systems biology [PDF]
, 2004 Progress in the study of biological systems such as the heart, brain, and liver will require computer scientists to work closely with life scientists and mathematicians.
Margoninski, O. +7 more
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Bridging the gap between systems biology and synthetic biology
Frontiers in Microbiology, 2013 Systems biology is an inter-disciplinary science that studies the complex interactions and the collective behavior of a cell or an organism. Synthetic biology, as a technological subject, combines biological science and engineering, allowing the design ...
Di eLiu +2 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Computational systems biology /
, 2014 This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as ...
Kriete, Andres., Eils, Roland.
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
iScience, 2020 Summary: Ex vivo human tumor models have emerged as promising, yet complex tools to study cancer immunotherapy response dynamics. Here, we present a strategy that integrates empirical data from an ex vivo human system with computational models to ...
Munisha Smalley +17 more
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Perspectives in systems biology [PDF]
Systems and Synthetic Biology, 2014 For this special issue, I have hopefully been able to assemble an assortment of diverse and interesting articles reflecting the wide range of phenomena where systems biology approaches are being successfully applied. This issue has nine papers containing contributions from twenty six researchers.
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