Results 221 to 230 of about 25,508,313 (370)

Frontiers of Plant Cell Biology: Signals and Pathways, System-Based Approaches 22nd Symposium in Plant Biology (University of California—Riverside) [PDF]

, 2003
Peter V. Minorsky
openalex   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

NKG2D-CAR-targeted iPSC-derived MSCs efficiently target solid tumors expressing NKG2D ligand

iScience
Summary: Mesenchymal stem cells (MSCs) hold potential in cancer therapy; however, insufficient tumor homing ability and heterogeneity limit their therapeutic benefits.
Shuqing Tang, Yusang Zhang, Peiyun Wang, Qiyu Tang, Yating Liu, Fan Lu, Mengting Han, Miaojin Zhou, Qian Hu, Mai Feng, Desheng Liang   +10 more
doaj  

Challenges and opportunities in systems biology education. [PDF]

Endocr Relat Cancer
Didier J, Croce S, Bayoumi S, Valceschini E, Escoffier H, Gonzalez E, Kishk A, Badkas A, De Landtsheer S, Sauter T.   +9 more
europepmc   +1 more source

Cavefish as a Model System in Evolutionary Developmental Biology

, 2001
William R. Jeffery
openalex   +1 more source

Achieving the in Silico Plant. Systems Biology and the Future of Plant Biological Research [PDF]

, 2003
Peter V. Minorsky
openalex   +1 more source

A methodology for performing global uncertainty and sensitivity analysis in systems biology.

Journal of Theoretical Biology, 2008
Simeone Marino, Ian B. Hogue, Christian J Ray, D. Kirschner   +3 more
semanticscholar   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Telomere Lengths and Telomerase Activity in Dog Tissues: A Potential Model System to Study Human Telomere and Telomerase Biology

, 2001
Lubna Nasir, Pauline Devlin, Tom P. McKevitt, Gerard R. Rutteman, David J. Argyle   +4 more
openalex   +1 more source

Harvard heralds fresh take on systems biology [PDF]

, 2003
Erika Check
openalex   +1 more source