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Systems biology of tuberculosis
Tuberculosis, 2011Systems biology seeks to study biological systems as a whole, by adopting an integrated approach to study and understand the function of biological systems, particularly, the response of such systems to various perturbations. In this article, we focus on the Indian efforts towards systems-level studies of Mycobacterium tuberculosis and its interaction ...
Chandra, Nagasuma +2 more
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Systems biology of the mitochondrion
American Journal of Physiology-Cell Physiology, 2006The promise of the current era of biological research is to understand the integrated function of biological systems in order to predict and rationally manipulate their behavior, with the ultimate aim of improving human health.
Daniel A, Beard, Marko, Vendelin
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The Language of Systems Biology
2014Systems Biology is an interdisciplinary approach to understand biological processes that act on different scales. For example biochemical pathways steer internal cell dynamics, which can lead to cell movement. Cell movement can lead to cancer invasion and cancer invasion can lead to a disease that affects the whole body. To understand such a process, a
DELITALA, MARCELLO EDOARDO, T. Hillen
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Nature Methods, 2006
A web and print Focus on systems biology from Nature Publishing Group provides a practical introduction to a field that for all its promise still has many skeptics.
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A web and print Focus on systems biology from Nature Publishing Group provides a practical introduction to a field that for all its promise still has many skeptics.
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The Biology of the Immune System
JAMA: The Journal of the American Medical Association, 1997Intact immunity is fundamental for survival. The human immune system has evolved with the sophisticated biologic capacity to distinguish self from nonself and for memory through the process of clonal expansion. The ability to distinguish even subtle differences from self, and among myriad antigens, is possible by the rearrangement of genes that encode ...
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Annual Review of Biochemistry, 2017
Metabolism is highly complex and involves thousands of different connected reactions; it is therefore necessary to use mathematical models for holistic studies. The use of mathematical models in biology is referred to as systems biology. In this review, the principles of systems biology are described, and two different types of mathematical models ...
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Metabolism is highly complex and involves thousands of different connected reactions; it is therefore necessary to use mathematical models for holistic studies. The use of mathematical models in biology is referred to as systems biology. In this review, the principles of systems biology are described, and two different types of mathematical models ...
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A census of pathway maps in cancer systems biology
Nature Reviews Cancer, 2020Brent M Kuenzi +2 more
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A road map for the development of community systems (CoSy) biology
Nature Reviews Microbiology, 2012Karsten Zengler +2 more
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The second wave of synthetic biology: from modules to systems
Nature Reviews Molecular Cell Biology, 2009Ron Weiss, Weiss Ron
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From genotype to phenotype: can systems biology be used to predict Staphylococcus aureus virulence?
Nature Reviews Microbiology, 2012Nicholas K Priest +2 more
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