Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Systems biology modelling based evaluation of omega-3 formulation in managing cardiovascular and cerebrovascular risk. [PDF]
Balakrishnan S +6 more
europepmc +1 more source
Advancing toxicity AI-based prediction with multilevel systems biology: a case study on genotoxicity. [PDF]
Zhang X +7 more
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Systems Biology Applications in Revealing Plant Defense Mechanisms in Disease Triangle. [PDF]
Akter T +4 more
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A systems biology approach to identify key targets in KRAS/BRAF-mutated colorectal cancer. [PDF]
Shiravi S +6 more
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Decoding the interplay between COVID-19 and diabetic nephropathy through bioinformatics and systems biology techniques. [PDF]
Chen X, Zeng Q, Xia M, Chen Y.
europepmc +1 more source
Systems biology approach uncovers candidates for kidney-heart interorgan crosstalk after myocardial infarction. [PDF]
Wolf H +10 more
europepmc +1 more source
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