Results 91 to 100 of about 1,058,962 (296)

VISUAL MODELS OF SYSTEMS ENGINEERING OF ADDITIVE MANUFACTURING PROCESSES

Надежность и качество сложных систем
Background. The paper discusses methods for using visual systems engineering tools using the example of additive manufacturing processes. Materials and methods.
A.I. Vlasov, G.A. Volkov, K.V. Selivanov
doaj   +1 more source

Hybrid Space and Submarine Architecture to Ensure Information Security of Telecommunications (HEIST)

IEEE Access
Undersea communication cables (UCCs) are critical for global connectivity but remain vulnerable to physical and cyber threats. This paper presents insights from the NATO Science for Peace and Security Project: Hybrid Space and Submarine Architecture to ...
Nicolo Boschetti, Anurag Koyyada, Barrett Downs, William Rosenthal, Nathaniel Gordon, Hans Liwang, Alexander Marder, Johan Sigholm, Oskar Franberg, Jonas Kindgren, Thomas Frisk, Bjarni Mar Magnusson, Myriam Dunn Cavelty, Henric Johnson, Gregory Falco   +14 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

A PREDICTIVE MAINTENANCE APPROACH FOR COMPLEX EQUIPMENT BASED ON A FAILURE MECHANISM PROPAGATION MODEL

International Journal of Prognostics and Health Management, 2019
The aim of this paper is to propose a comprehensive approach for the predictive maintenance of complex equipment. The approach relies on a physics of failure ( PoF ) model based on expert knowledge and data.
Olivier Blancke, Amélie Combette, Normand Amyot, Dragan Komljenovic, Mélanie Lévesque, Claude Hudon, Antoine Tahan, Noureddine Zerhouni   +7 more
doaj   +1 more source

Floquet engineering of classical systems [PDF]

, 2018
Sho Higashikawa, Hiroyuki Fujita, Masahiro Sato   +2 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Improving Decision Quality in High-Tech System Design: An In-Depth Study Leveraging Industry Expertise

Systems
Technological advancement is driven by the development of high-tech systems. However, growing demands on technology lead to more system complexity and to complexity in developing organizations.
Jan A. Lenssen, Kostas Nizamis, G. Maarten Bonnema   +2 more
doaj   +1 more source

Floquet Hamiltonian Engineering of an Isolated Many-Body Spin System

, 2021
Sebastian Geier, Nithiwadee Thaicharoen, Clément Hainaut, Titus Franz, Andre Salzinger, Annika Tebben, David Grimshandl, G. Zürn, Weidemüller Matthias   +8 more
openalex   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Marine diesel engine reliable intelligent fault diagnosis method based on the generalized multi-source information fusion

iScience
Summary: Diesel engines provide essential power and energy guarantee for vessels. Due to scarce fault samples and complex parameter-fault coupling, traditional methods struggle in marine diesel engine diagnosis, underscoring the need for reliable ...
Zaimi Xie, Chunmei Mo, Baozhu Jia
doaj   +1 more source