Results 91 to 100 of about 4,929,681 (330)

Semantic Priority Navigation for Energy-Aware Mining Robots

open access: yesSystems
Autonomous navigation in subterranean mines is hindered by deformable terrain, dust-laden visibility, and densely packed, safety-critical machinery. We propose a systems-oriented navigation framework that embeds semantic priorities into reactive planning
Claudio Urrea   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

OVERVIEW OF AUTOMATION METHODS OF SMALL AND MEDIUM ENGINEERING ENTERPRISES BASED ON CALS-TECHNOLOGIES AND SYSTEMS ENGINEERING APPROACH

open access: yesВестник Донского государственного технического университета, 2018
The design techniques of integrated information systems development aimed at the life cycle support are reviewed. Cases of the CALS-technologies and systems engineering for building some typical models are considered. These models can be used for typical
Dmitry V. DUDKIN
doaj  

Engaging the International Heritage Community to Validate End-User Requirements for Historic Building Information Modelling

open access: yesApplied Sciences
Historic Building Information Modelling (HBIM) is the application of BIM, an information management and modelling process, to cultural heritage (CH) assets.
Lucy J. Lovell   +2 more
doaj   +1 more source

On the engineering of systems of systems: key challenges for the requirements engineering community! [PDF]

open access: yes
Software intensive systems of the future will be ultra large-scale systems of systems. Systems of Systems Engineering focuses on the interoperation of many independent, self-contained constituent systems to achieve a global need. The scale and complexity
Ncube, Cornelius
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

An Analytical Framework for Determining the Minimum Size of Highly Miniaturized Satellites: PlanarSats

open access: yesAerospace
This paper introduces a power-driven systems engineering methodology for the early-phase design of highly miniaturized satellites: PlanarSats. We derive an analytical framework linking power requirements, contingency policies, solar-cell performance, and
Mehmet Şevket Uludağ   +1 more
doaj   +1 more source

Agent Based Approaches to Engineering Autonomous Space Software

open access: yes, 2010
Current approaches to the engineering of space software such as satellite control systems are based around the development of feedback controllers using packages such as MatLab's Simulink toolbox.
Dennis, Louise A.   +4 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Power Contingency/Margin Methodology and Operational Envelope Analysis for PlanarSats

open access: yesAerospace
This paper presents a power-centric systems-engineering approach for PlanarSats and for atto-, and femto-class spacecraft where surface-limited power dominates design.
Mehmet Şevket Uludağ   +1 more
doaj   +1 more source

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