Results 81 to 90 of about 13,668,708 (244)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Journal of Management & Engineering Integration, v.18, no.1 (Summer)
Published in SOAR: Shocker Open Access Repository by the Wichita State University Libraries Technical Services, August 2025.Copyright of the Journal of Management and Engineering Integration is the property of the Association of Industry, Engineering and
Association for Industry, Engineering and Management Systems (AIEMS)
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Reengineering Systems Engineering [PDF]
, 2009 Proceedings of the 3rd Asia-Pacific Conference on Systems Engineering (APCOSE), Singapore, 2009This paper documents (1) the early phases of using systems engineering to develop a conceptual system – the system being developed is a systems engineering ...
Kasser, Joseph +2 more
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Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
APPLYING MODEL-BASED SYSTEMS ENGINEERING TO BASELINE HUGHES SALVO MODEL FOR FUTURE DEVELOPMENT
This capstone project explores how model-based systems engineering (MBSE) principles can be applied to facilitate modifications to the Hughes Salvo model and how the development of a baseline set of systems engineering artifacts can aid in future ...
Doerr, Christopher M. +4 more
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
A Guide for Systems Engineering Graduate Work: How to write well and make your critical thinking visible [PDF]
, 2017 Version 2.0This guide is designed to help students communicate effectively in writing.
Systems Engineering Department
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FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source