Results 61 to 70 of about 1,468,527 (267)
International Conference on Industry, Engineering, and Management Systems (2013 : Cocoa Beach, Fla.)
, 2013 Published in SOAR: Shocker Open Access Repository by Wichita State University Libraries Technical Services, May 2022.The IEMS'13 conference committee: The Association for Industry, Engineering, & Management Systems (Sponsor); Nael Aly (Conference Co ...
International Conference on Industry, Engineering, and Management Systems
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
UNMANNED UNDERWATER VEHICLE MISSION SYSTEMS ENGINEERING PRODUCT REUSE RETURN ON INVESTMENT [PDF]
, 2022 Unmanned Underwater Vehicles (UUVs) accomplish a wide spectrum of missions ranging from generic to extremely specific. Although not all UUVs can accomplish all missions, there is significant replication of the requirements and the systems across the ...
Haller, Kristina +4 more
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
International Conference on Industry, Engineering, and Management Systems 2016
, 2016 Published in SOAR: Shocker Open Access Repository by Wichita State University Libraries Technical Services, May 2022.The IEMS'16 conference committee: Nael Aly (Conference Co-Chair); Ahmad Elshennawy (Conference Co-Chair); Jordan Green (Program Chair ...
International Conference on Industry, Engineering, and Management Systems
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Reengineering Systems Engineering [PDF]
, 2009 Proceedings of the 3rd Asia-Pacific Conference on Systems Engineering (APCOSE), Singapore, 2009This paper documents (1) the early phases of using systems engineering to develop a conceptual system – the system being developed is a systems engineering ...
Kasser, Joseph +2 more
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Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
International Conference on Industry, Engineering, and Management Systems 2025
Published in SOAR: Shocker Open Access Repository by Wichita State University Libraries Technical Services, November 2025. 2025 IEMS Officers: Gamal Weheba (Conference Chair); Hesham Mahgoub (Program Chair); Dalia Mahgoub (Technical Director); Ed Sawan ...
International Conference on Industry, Engineering, and Management Systems
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