Results 111 to 120 of about 4,929,681 (330)

ALCEA: The Architecture Life-Cycle Effect Analysis Method

IEEE Open Journal of Systems Engineering
This article describes the architecture life cycle effect analysis (ALCEA) method, a structured method for evaluating proposed new architectures for software-intensive systems. The method evaluates a proposed architecture by quantifying its effect on the
Jakob Axelsson, Damir Bilic, Daniel Brahneborg, Joakim Froberg, Henrik Gustavsson, Robbert Jongeling, Daniel Sundmark   +6 more
doaj   +1 more source

Self-replicating systems: A systems engineering approach [PDF]

A first approach to conceptualize self-replicating systems was developed from past and present abstract theories. The engineering elements of self-replicating systems are defined in terms of a basic reference system. A number of options are investigated.
Darbro, W. A., Vontiesenhausen, G.
core   +1 more source

Sensor & instrumentation system : series 2 [PDF]

, 2017
This book is an introduction to a number of the topics in sensor and instrumentation systems. Many of the topics describe the design experiments and system measurement especially in sensor applications.

core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

A Qualitative Study of Factors That Influence Older Adults' Work on the Arduous Path to Spine Surgery

Health Science Reports
Background and Aims Older adults worldwide are increasingly diagnosed with degenerative spine disease (DSD). Although older adults are frequently interacting with the healthcare system, clinicians are likely not aware of the many health‐related ...
Andrea L. Strayer, Samantha Bjornson, Nicole E. Werner, Anna Krupp   +3 more
doaj   +1 more source

Advanced engineering - Communications systems research [PDF]

Communications systems research on information systems and on digital telemetry and command in Deep Space ...

core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Towards a Theory of Systems Engineering Processes: A Principal-Agent Model of a One-Shot, Shallow Process

, 2019
Systems engineering processes coordinate the effort of different individuals to generate a product satisfying certain requirements. As the involved engineers are self-interested agents, the goals at different levels of the systems engineering hierarchy ...
Bilionis, Ilias, Panchal, Jitesh, Safarkhani, Salar   +2 more
core  

3rd Workshop on Avionics Systems and Software Engineering (AvioSE’21)

, 2021
Björn Annighöfer, Andreas Schweiger, Marina Reich   +2 more
openalex   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source