Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Book Review: Passive Energy Dissipation Systems in Structural Engineering, by T. T. Soong and G. F. Dargush, Wiley, Chichester, ISBN: 0-471-96821-8, No. of pages: 356 [PDF]
, 1998 James M. Kelly
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Decision-Making Framework of Requirement Engineering Barriers in the Domain of Global Healthcare Information Systems [PDF]
, 2022 Muhammad Hamza +6 more
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Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Engineering a nanoantibiotic system displaying dual mechanism of action [PDF]
Huihua Xing +6 more
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New Horizons in Electrochemical Science and Technology, National Materials Advisory Board, Commission on Engineering and Technical Systems, National Research Council (National Academy Press, 1986) [PDF]
, 1988 Ronald B. Diegle
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Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
The systems engineering approach to quality improvement in the NHS. [PDF]
Future Healthc J, 2022 Chada BV.
europepmc +1 more source
Innovative Educational Technology for the Use of Modern CAD Systems for the Formation of Professional Competences of Students of Radio Engineering Specialties [PDF]
, 2020 Victor B. Suchkov +3 more
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Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source