Results 141 to 150 of about 4,654,755 (329)

User engineering principles for interactive systems [PDF]

, 1971
Wilfred J. Hansen
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Systems Engineering Approach to Modeling and Analysis of Chronic Obstructive Pulmonary Disease. [PDF]

ACS Omega, 2023
Kurian V, Ghadipasha N, Gee M, Chalant A, Hamill T, Okossi A, Chen L, Yu B, Ogunnaike BA, Beris AN.   +9 more
europepmc   +1 more source

Engineering Design Handbook. Computer Aided Design of Mechanical Systems [PDF]

, 1973
Jr Haug, J. Edward
openalex   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

The systems engineering approach to quality improvement in the NHS. [PDF]

Future Healthc J, 2022
Chada BV.
europepmc   +1 more source

Applications of a numerical geometry system in engineering [PDF]

, 1976
Jerry Mayfield, R. M. Burkley
openalex   +1 more source

Engineering Cell Systems

Stem Cells International, 2019
Tiago G. Fernandes, Ricardo P. Baptista, Howard Kim   +2 more
openaire   +3 more sources

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Open-Source Data Formalization through Model-Based Systems Engineering for Concurrent Preliminary Design of CubeSats

Aerospace
Market trends in the space sector suggest a notable increase in satellite operations and market value for the coming decade. In parallel, there has been a shift in the industrial and academic sectors from traditional Document-Based System Engineering to ...
Giacomo Luccisano, Sophia Salas Cordero, Thibault Gateau, Nicole Viola   +3 more
doaj   +1 more source