Results 141 to 150 of about 4,318,020 (230)

How systems engineering can improve care in the ICU. [PDF]

J Clin Anesth, 2020
Lecamwasam H, Lytle F, Popovich M, Sunshine J, Pronovost P.   +4 more
europepmc   +1 more source

Using the Systems Engineering Initiative for Patient Safety (SEIPS) model to describe the planning and management of the COVID-19 pandemic in Hong Kong. [PDF]

Int J Qual Health Care, 2021
Kwan WM, Mok CK, Kwok YT, Ling H, Lam HW, Law TH, Leung PM, Mak MY, Que TL, Kan CH, Tang YH.   +10 more
europepmc   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Optimising HIV drug resistance testing laboratory networks in Kenya: insights from systems engineering modelling. [PDF]

BMJ Open
Wang Y, Kingwara L, Wagner AD, Yongo N, Hassan SA, Liu S, Oyaro P, Patel RC.   +7 more
europepmc   +1 more source

Adaptive Content Tuning of Social Network Digital Health Interventions Using Control Systems Engineering for Precision Public Health: Cluster Randomized Controlled Trial.

J Med Internet Res, 2023
Rocha P, Pinheiro D, de Paula Monteiro R, Tubert E, Romero E, Bastos-Filho C, Nuno M, Cadeiras M.   +7 more
europepmc   +1 more source

Coronavirus disease 2019 (COVID-19) and antibiotic stewardship: Using a systems engineering approach to maintain patient safety. [PDF]

Infect Control Hosp Epidemiol, 2021
Keating JA, McKinley L, Safdar N.
europepmc   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Environmental cleaning and disinfection in the operating room: a systematic scoping review through a human factors and systems engineering lens. [PDF]

Infect Control Hosp Epidemiol
Xie A, Sax H, Daodu O, Alam L, Sultan M, Rock C, Stewart CM, Perry SJ, Gurses AP.   +8 more
europepmc   +1 more source