Results 91 to 100 of about 291,090 (273)
The immunological function of GABAergic system
Frontiers in Bioscience, 2017 As a well-known inhibitory neurotransmitter in the central nervous system, gamma-aminobutyric acid also has critical roles in immune system. Immune cells (e.g., lymphocytes, macrophages) express the components of GABAergic system, including GABA receptors, GABA transporters, and GABA metabolic enzymes.
Chenlu, Wu +5 more
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FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
The Immunological Synapse--a Multitasking System
Science, 2002 The immunological synapse, the interface between the T cell and antigen-presenting cell (APC), is thought to be important for enhancing and sustaining signaling by the T cell receptor after it has engaged antigenic peptide on the APC surface. In a Perspective, van der Merwe and Davis discuss new findings ( Lee et al.) demonstrating ...
Van Der Merwe, P, Davis, S
openaire +2 more sources
New Horizons in Food Science via Agricultural Immunity
, 2020 Agricultural immunology is a new research field that fuses animal, marine and plant immunology, all of which have been previously regarded as separate topics and fields.
core +2 more sources
FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
Integrating immunology and microfluidics for single immune cell analysis [PDF]
, 2018 The field of immunoengineering aims to develop novel therapies and modern vaccines to manipulate and modulate the immune system and applies innovative technologies toward improved understanding of the immune system in health and disease.
Tel, Jurjen +8 more
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FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Assessing the performance of the resource limited artificial immune system AINE [PDF]
, 2001 This report presents an assessment of the resource limited artificial immune system known as AINE. This work is a continuation of previous work to develop an artificial immune system for data analysis.
Timmis, Jon, Knight, Thomas
core
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
FEBS Open Bio, EarlyView.We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source