Results 31 to 40 of about 291,090 (273)
Editorial: "AAV Gene Therapy: Immunology and Immunotherapeutics"
, 2021 Editorial on the Research Topic: AAV Gene Therapy: Immunology and ...
Gao, Guangping +2 more
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Predictive Markers of Immunogenicity and Efficacy for Human Vaccines
Vaccines, 2021 Vaccines represent one of the major advances of modern medicine. Despite the many successes of vaccination, continuous efforts to design new vaccines are needed to fight “old” pandemics, such as tuberculosis and malaria, as well as emerging pathogens ...
Matthieu Van Tilbeurgh +10 more
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The Self Model and the Conception of Biological Identity in Immunology [PDF]
, 2005 The self/non-self model, first proposed by F.M. Burnet, has dominated immunology for sixty years now. According to this model, any foreign element will trigger an immune reaction in an organism, whereas endogenous elements will not, in normal ...
Pradeu, Thomas +5 more
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eLife, 2014 Variability within isogenic T cell populations yields heterogeneous ‘local’ signaling responses to shared antigenic stimuli, but responding clones may communicate ‘global’ antigen load through paracrine messengers, such as cytokines. Such coordination of
Karen E Tkach +10 more
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Frontiers in Immunology, 2021 BackgroundThe recent emergence of COVID-19, rapid worldwide spread, and incomplete knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited development of therapeutic strategies.
Aliakbar Hasankhani +11 more
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Systems Immunology Approaches to Metabolism
Annual Review of Immunology, 2023 Over the last decade, immunometabolism has emerged as a novel interdisciplinary field of research and yielded significant fundamental insights into the regulation of immune responses. Multiple classical approaches to interrogate immunometabolism, including bulk metabolic profiling and analysis of metabolic regulator expression, paved the way to ...
Denis A, Mogilenko +2 more
openaire +2 more sources
Multi-Omics Approaches in Immunological Research
Frontiers in Immunology, 2021 The immune system plays a vital role in health and disease, and is regulated through a complex interactive network of many different immune cells and mediators. To understand the complexity of the immune system, we propose to apply a multi-omics approach
Xiaojing Chu +13 more
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Philosophy of Immunology [PDF]
, 2019 Immunology is central to contemporary biology and medicine, but it also provides novel philosophical insights. Its most significant contribution to philosophy concerns the understanding of biological individuality: what a biological individual is, what ...
Pradeu, Thomas
core +1 more source
Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum
eLife, 2021 Falciparum malaria is clinically heterogeneous and the relative contribution of parasite and host in shaping disease severity remains unclear. We explored the interaction between inflammation and parasite variant surface antigen (VSA) expression, asking ...
Kathryn Milne +20 more
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A Peripheral Immune Signature of Labor Induction
Frontiers in Immunology, 2021 Approximately 1 in 4 pregnant women in the United States undergo labor induction. The onset and establishment of labor, particularly induced labor, is a complex and dynamic process influenced by multiple endocrine, inflammatory, and mechanical factors as
Kazuo Ando +22 more
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