Results 161 to 170 of about 4,023,339 (305)

Beyond Compliance: Identifying High-Performance Models and Critical Success Factors for Integrated Management System Effectiveness (A Systematic Review)

Ianna Journal of Interdisciplinary Studies
Background: Organisations' interest in integrating management systems has emerged as a key strategy for improving organisational performance. Finding a model that fits the organisation's needs and optimises activities with the greatest possible benefit ...
Jesús Enrique Osorio Romero, Dina Luz Castro Páez, Braian López Ossa, Mabel Ibarra Luna   +3 more
doaj  

Integrating Large Language Models into Traffic Systems: Integration Levels, Capability Boundaries, and an Information-Theoretic Perspective. [PDF]

Entropy (Basel)
Tu W, Li J, Xiao F, Wang X, Lu Y.
europepmc   +1 more source

Smart Cell Culture Systems: Integration of Sensors and Actuators into Microphysiological Systems. [PDF]

ACS Chem Biol, 2018
Modena MM, Chawla K, Misun PM, Hierlemann A.   +3 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Techno-economic analysis for a 100% renewable hybrid energy systems integration in a research facility in Morocco. [PDF]

iScience
Choukri NE, Touili S, Azzaoui A, Alami Merrouni A.   +3 more
europepmc   +1 more source

Indicators and Measurement Tools for Health Systems Integration: A Knowledge Synthesis. [PDF]

Int J Integr Care, 2017
Suter E, Oelke ND, da Silva Lima MAD, Stiphout M, Janke R, Witt RR, Van Vliet-Brown C, Schill K, Rostami M, Hepp S, Birney A, Al-Roubaiai F, Marques GQ.   +12 more
europepmc   +1 more source

Integrated Information Systems [PDF]

Yearbook of Medical Informatics, 1993
openaire   +2 more sources

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Potential benefits and human systems integration of parastronauts with bilateral vestibulopathy for a space mission. [PDF]

Front Neurol
Ramsburg CF, Wood SJ, Lackner JR, Moynihan S, Reschke MF, Denise P, Clément G.   +6 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source