Results 171 to 180 of about 4,023,339 (305)

Public Health Workforce Professional Development Analysis: A Human-Systems Integration for Healthy Communities. [PDF]

Int J Public Health
Osnat B, Orna BE, Tomasz B, Kasia C, Nadav D, Jascha N, Keren D, Mariusz D, Janas H, Lore L, Hagai L, Fiona M, Maureen M, Zohar M, Yehuda N, Leah OE, Robert O, Stephanie PB, Maya PR, Theodore T, Shira ZS, Paul B.   +21 more
europepmc   +1 more source

Highlights from the First Annual Spinal Navigation, Emerging Technologies and Systems Integration Meeting. [PDF]

Ann Transl Med, 2018
Drazin D, Grunert P, Hartl R, Polly D, Meyer B, Catchpole K, Laufer I, Sethi R, Perry T, Simon D, Wang M, Fisher C, Scribner M, White G, Tubbs RS, Oskouian RJ, Kim T, Johnson JP.   +17 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Achieving COVID-19 and Routine Immunization Data Systems Integration on the Electronic Management of Immunization Data System in Nigeria. [PDF]

Glob Health Sci Pract
Tella-Lah T, Akinleye D, Aliyu AS, Falodun T, Okpere S, Akpan D, Orefunwa O, Metiboba L, Owoicho J, Okposen B, Nwabufo A.   +10 more
europepmc   +1 more source

Clinical Information Systems Integration in New York City's First Mobile Stroke Unit. [PDF]

Appl Clin Inform, 2018
Kummer BR, Lerario MP, Navi BB, Ganzman AC, Ribaudo D, Mir SA, Pishanidar S, Lekic T, Williams O, Kamel H, Marshall RS, Hripcsak G, Elkind MSV, Fink ME.   +13 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Health systems integration: competing or shared mental models? [PDF]

Int J Integr Care, 2014
Evans JM.
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Enhancing Surveillance Systems: Integration of Object, Behavior, and Space Information in Captions for Advanced Risk Assessment. [PDF]

Sensors (Basel)
Jeon M, Ko J, Cheoi K.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source