Results 171 to 180 of about 12,378,837 (298)

Public Health Workforce Professional Development Analysis: A Human-Systems Integration for Healthy Communities. [PDF]

Int J Public Health
Osnat B, Orna BE, Tomasz B, Kasia C, Nadav D, Jascha N, Keren D, Mariusz D, Janas H, Lore L, Hagai L, Fiona M, Maureen M, Zohar M, Yehuda N, Leah OE, Robert O, Stephanie PB, Maya PR, Theodore T, Shira ZS, Paul B.   +21 more
europepmc   +1 more source

Highlights from the First Annual Spinal Navigation, Emerging Technologies and Systems Integration Meeting. [PDF]

Ann Transl Med, 2018
Drazin D, Grunert P, Hartl R, Polly D, Meyer B, Catchpole K, Laufer I, Sethi R, Perry T, Simon D, Wang M, Fisher C, Scribner M, White G, Tubbs RS, Oskouian RJ, Kim T, Johnson JP.   +17 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Clinical Information Systems Integration in New York City's First Mobile Stroke Unit. [PDF]

Appl Clin Inform, 2018
Kummer BR, Lerario MP, Navi BB, Ganzman AC, Ribaudo D, Mir SA, Pishanidar S, Lekic T, Williams O, Kamel H, Marshall RS, Hripcsak G, Elkind MSV, Fink ME.   +13 more
europepmc   +1 more source

Integrated Information Systems [PDF]

Yearbook of Medical Informatics, 2000
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Achieving COVID-19 and Routine Immunization Data Systems Integration on the Electronic Management of Immunization Data System in Nigeria. [PDF]

Glob Health Sci Pract
Tella-Lah T, Akinleye D, Aliyu AS, Falodun T, Okpere S, Akpan D, Orefunwa O, Metiboba L, Owoicho J, Okposen B, Nwabufo A.   +10 more
europepmc   +1 more source

Health systems integration: competing or shared mental models? [PDF]

Int J Integr Care, 2014
Evans JM.
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Enhancing Surveillance Systems: Integration of Object, Behavior, and Space Information in Captions for Advanced Risk Assessment. [PDF]

Sensors (Basel)
Jeon M, Ko J, Cheoi K.
europepmc   +1 more source