Results 141 to 150 of about 37,129,814 (295)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

A Systematic Review of Systems Science Approaches to Understand and Address Domestic and Gender-Based Violence. [PDF]

open access: yesJ Fam Violence, 2023
Tracy M   +5 more
europepmc   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Identifying opportunities for collective action around community nutrition programming through participatory systems science. [PDF]

open access: yesCancer Causes Control, 2023
Chebli P   +9 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Energy Systems Thermal Plant

open access: yes, 1970
aerial view, Energy Systems is a steam and chilled water thermal energy company in Omaha, Nebraska., 6/19 ...
Energy Systems
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The System of Sciences

open access: yes
This is the accreditation of the system of new appliwerd chemistry in 2025 for the new applications in applied chemistry for the sciences as a one pakage of the sciences in the studies this accreditation by Abdul Kareem Oath for the Sciences of everythuing about everything as a one stage nvalue for accredited zero system dfor the highest level of the ...
openaire   +2 more sources

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