Participatory systems science for enhancing health and wellbeing in the Indian Ocean territories. [PDF]
Allender S +3 more
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
A Systematic Review of Systems Science Approaches to Understand and Address Domestic and Gender-Based Violence. [PDF]
Tracy M +5 more
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Identifying opportunities for collective action around community nutrition programming through participatory systems science. [PDF]
Chebli P +9 more
europepmc +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
aerial view, Energy Systems is a steam and chilled water thermal energy company in Omaha, Nebraska., 6/19 ...
Energy Systems
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Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Teaching Systems-Thinking Concepts with Hypothetical Case Scenarios: An Exploration in Food-Systems Science Education. [PDF]
Sanders CE +5 more
europepmc +1 more source
This is the accreditation of the system of new appliwerd chemistry in 2025 for the new applications in applied chemistry for the sciences as a one pakage of the sciences in the studies this accreditation by Abdul Kareem Oath for the Sciences of everythuing about everything as a one stage nvalue for accredited zero system dfor the highest level of the ...
openaire +2 more sources

