Results 131 to 140 of about 2,984,717 (307)
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Human Performance in Information Transmission: Part III [PDF]
Made available in DSpace on 2015-04-06T20:44:35Z (GMT). No. of bitstreams: 2 license.txt: 4922 bytes, checksum: 910b249b4beec47e7ab768910c8f966f (MD5) B1-68.pdf: 52723739 bytes, checksum: 974135f82cb4b86fe8e6ec999a7fb98e (MD5) Previous issue date: 1955-
Staff and Consultants, Bio-Systems Group
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Meeting fundamental human needs while preserving Earth's life support systems will require an accelerated transition toward sustainability. A new field of sustainability science is emerging that seeks to understand the fundamental character of ...
Clark, W.C. +4 more
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Enhancing Practical Impact and Engagement in Design Science Research [PDF]
This paper addresses the gap between theoretical advances in Design Science Research (DSR) and their practical implementation. Despite DSR's potential for transformative impact, the challenge of translating research artifacts into tangible, real-world ...
Strohmann, Timo +3 more
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Integrating Systems Thinking and Behavioural Science
Traditional approaches to changing health behaviours have primarily focused on education and raising awareness, assuming that increased knowledge leads to better decisions.
John A. Parkinson +4 more
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Resilient Agrifood Systems Science Group: Evaluation Report, Annexes [PDF]
The CGIAR 2030 Research and Innovation Strategy sets priorities to deliver solutions for development through 33 initiatives across three interlinked action areas: Systems Transformation, Resilient Agrifood Systems (RAFS), and Genetic Innovation. The RAFS
Fakoya, K. +4 more
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