Results 41 to 50 of about 694,403 (269)

Characteristics of Traffic Flow at Nonsignalized T-Shaped Intersection with U-Turn Movements

open access: yesThe Scientific World Journal, 2013
Most nonsignalized T-shaped intersections permit U-turn movements, which make the traffic conditions of intersection complex. In this paper, a new cellular automaton (CA) model is proposed to characterize the traffic flow at the intersection of this type.
Hong-Qiang Fan   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Optimization of Classification Track Assignment Considering Block Sequence at Train Marshaling Yard

open access: yesJournal of Advanced Transportation, 2018
An operational process at train marshaling yard is considered in this study. The inbound trains are decoupled and disassembled into individual railcars, which are then moved to a series of classification tracks, forming outbound trains after being ...
Yingqun Zhang   +4 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Timetable Optimization of Rail Transit Loop Line with Transfer Coordination

open access: yesDiscrete Dynamics in Nature and Society, 2016
In an urban rail transit system, it is important to coordinate the timetable of a loop line with its connecting lines so as to reduce the waiting time of passengers.
Rui-Jia Shi   +4 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Dynamic Route Choice Prediction Model Based on Connected Vehicle Guidance Characteristics

open access: yesJournal of Advanced Transportation, 2017
A route choice prediction model is proposed considering the connected vehicle guidance characteristics. This model is proposed to prevent the delay in the release of guidance information and route planning due to inaccurate timing predictions of the ...
Jiangfeng Wang   +3 more
doaj   +1 more source

Control and Guidance of Low-Cost Robots via Gesture Perception for Monitoring Activities in the Home

open access: yesSensors, 2015
This paper describes the development of a low-cost mini-robot that is controlled by visual gestures. The prototype allows a person with disabilities to perform visual inspections indoors and in domestic spaces. Such a device could be used as the operator'
Angel D. Sempere   +4 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

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