Results 281 to 290 of about 323,783 (333)

Using non‐linear slide decks to administer individualized problem‐based learning assessments within pharmacology education

British Journal of Clinical Pharmacology, EarlyView.
Aim Problem‐based learning (PBL) is an established approach in medical, nursing, pharmacy and veterinary medicine education. This study describes the implementation and aims to evaluate the use of non‐linear slide decks as a method to deliver PBL as individualized student assessments within pharmacology education. This approach, originally developed in
Wendy R. Francis, Nia A. Davies, Aidan Seeley   +2 more
wiley   +1 more source

Adverse immunostimulation in early phase clinical trials: Key findings and recommendations based on the investigator's clinical experience

British Journal of Clinical Pharmacology, EarlyView.
Problem setting The emergence of therapeutic proteins has coincided with an increase of acute adverse immunostimulation (AIS). AIS has occured in clinical trials despite compliance with regulatory guidelines on preclinical evaluation and its incidence is anticipated to increase even further.
Juliette A. van den Noort, Marella C. E. van Ruissen, Lisanne C. A. Smidt, Naomi B. Klarenbeek, Philip H. K. Kremer, Manon A. A. Jansen, Jacobus Burggraaf, Joop M. A. van Gerven, Matthijs Moerland   +8 more
wiley   +1 more source

Prosecuting Opioid Use, Punishing Rurality [PDF]

, 2019
Beety, Valena E.
core  

Evaluation of the Medicines and Healthcare products Regulatory Agency's introduction of a risk‐proportionate approach for clinical trials: An analysis of 4617 applications assessed between September 2023 and August 2024

British Journal of Clinical Pharmacology, EarlyView.
Aims The Medicines and Healthcare products Regulatory Agency (MHRA) introduced a risk‐proportionate approach to assess clinical trial applications for authorisation in August 2023. This study evaluates the impact of this approach on the timelines for reviewing proposals.
Andrea Manfrin, Kingyin Lee, Crina Cacou, James Pound, Anthony Harnden, June Raine, Munir Pirmohamed   +6 more
wiley   +1 more source

The OASIS Consortium: integrating multi-omics technologies to transform chemical safety assessment. [PDF]

Toxicol Sci
Rouquié D, Bender A, Cheah J, Crute CE, Dalmas D, Ewald J, Fullerton A, Harrill JA, Kadri S, Kleinstreuer N, Kramer N, LaRocca J, Mitchell CA, Seal S, Singh S, Carpenter AE.   +15 more
europepmc   +1 more source

National Mortality Databases to Assess Disease Burden in Systemic Autoimmune Diseases: A Valuable Resource But With Limitations

Arthritis &Rheumatology, EarlyView.
Ram Raj Singh
wiley   +1 more source

High-Throughput Toxicity Screening with <i>C. elegans</i>: Current Platforms, Key Advantages, and Future Directions. [PDF]

Environ Sci Technol
Crombie TA, Pamminger T, Andersen EC, Glaberman S.   +3 more
europepmc   +1 more source

The zebrafish in toxicology: a bibliometric analysis reveals current trends and future avenues for predictive safety assessment. [PDF]

Front Toxicol
Lima C, Gusso D, Disner GR, Pinto FJ, Falcão MAP, Rosa JGS, Lopes-Ferreira M.   +6 more
europepmc   +1 more source

Advances in Cytotoxicity Testing: From In Vitro Assays to In Silico Models. [PDF]

Int J Mol Sci
Ziemba B.
europepmc   +1 more source

BICLUSTERING METHODS FOR RE-ORDERING DATA MATRICES IN SYSTEMS BIOLOGY, DRUG DISCOVERY AND TOXICOLOGY

, 2010
Christodoulos A. Floudas
openalex   +1 more source