Results 131 to 140 of about 133,450 (199)

Macrophage PARP7 Alleviates Septic Cardiomyopathy by Interacting With TBK1 and Suppressing TBK1‐Driven Inflammatory Response

Advanced Science, EarlyView.
In septic cardiomyopathy, PARP7 directly binds TBK1 and mediates its ADP‐ribosylation, thereby repressing TBK1‐driven proinflammatory signaling in macrophages. ABSTRACT Septic cardiomyopathy is a life‐threatening complication of sepsis, and an uncontrolled inflammatory response represents a key pathogenic mechanism. PARP7 negatively regulates the IFN‐I
Jibo Han, Lintao Wang, Xin Zhong, Shenggang Zhao, Huihui Xie, Xue Han, Liming Lin, Yiting Lyu, Ke Xu, Jiajun Xu, Xiaowen Shi   +10 more
wiley   +1 more source

A single site, multi-operator precision study for second-generation HR-pQCT. [PDF]

JBMR Plus
Stapleton JR, Heilmann NZ, Cattell K, Burghardt AJ, Beavers DP, Madrid DA, Brandt KM, Delanie Lynch S, Weaver AA.   +8 more
europepmc   +1 more source

Biomimetic 3D Tactile Sensor System With Neuromorphic Encoding for Fascicle‐Level Feedback

Advanced Intelligent Systems, EarlyView.
A 3D biomimetic tactile sensor system converts skin‐like mechanical interactions into neural stimulation‐ready spike patterns. Embedded slow‐ and fast‐adapting sensors distinguish sustained pressure from transient touch, while neuromorphic encoding preserves their temporal signatures.
Minseok Kim, Jaeu Park, Minseok Kang, Yongwoo Kim, Sanghoon Lee   +4 more
wiley   +1 more source

Developing Orthoplastic Capacity for Soft-tissue Defects via Short-term Training: A Case Series in Samburu County, Kenya. [PDF]

Plast Reconstr Surg Glob Open
Sciuto D, MacKechnie MC, Terry MJ.
europepmc   +1 more source

Clinical Outcomes and Patient Experiences With Celiprolol Therapy in Vascular Ehlers–Danlos Syndrome: The First Non‐European Cohort

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Vascular Ehlers–Danlos syndrome (vEDS) is a hereditary connective tissue disorder caused by heterozygous pathogenic variants in COL3A1. European studies have shown that celiprolol may reduce the risk of life‐threatening vascular events, but outcomes in non‐European populations and the therapy's psychological impact remain unclear. We conducted
Megumi Furuhata‐Yoshimura, Tomomi Yamaguchi, Tomoki Kosho   +2 more
wiley   +1 more source

Patient-specific implants for joint-sparing reconstruction of segmental tibial and femoral defects : systematic literature review and introduction of a classification framework. [PDF]

Bone Joint Res
Buist ML, IJpma FFA, van Wees S, Meesters AML, Assink N, Jutte PC.   +5 more
europepmc   +1 more source

Musculoskeletal Phenotypes of 19 Patients With X‐Linked HNRNPH2‐Related Neurodevelopmental Disorder: A Prospective Case Series

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Detailed clinical phenotypes have been previously reported for 33 individuals with X‐linked HNRNPH2‐related neurodevelopmental disorder. Of these, 75% self‐reported a musculoskeletal abnormality, including hip dysplasia, scoliosis, kyphosis, lordosis, pes planus, arthritis, and missing spinous processes.
Ambar Garcia, Rachel Salazar, Nicole Holuba, Franklin E. Paulino, Michael G. Vitale, Jennifer M. Bain, Joshua Hyman   +6 more
wiley   +1 more source

Spider-Leg-Inspired Structural Design and Bézier Foot Trajectory Planning for Stable Walking of a Hexapod Robot. [PDF]

Biomimetics (Basel)
Wu J, Xiong Y, Shi H, Ning P, Li Z, Xu Z, Zhu J, Xia W.   +7 more
europepmc   +1 more source

A Novel Splice Variant in ERGIC1 Causes Arthrogryposis Multiplex Congenita—Characterization Using Urine‐Derived Cells

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis multiplex congenita (AMC) is defined as the presence of joint contractures affecting at least two body regions at birth. Three different ERGIC1 variants have been reported in individuals with AMC. Here, we report on a 16‐year‐old male with a homozygous ERGIC1 c.250+1G>A variant that was classified as a variant of uncertain ...
Lauren Kerr, Paul McKay, Juliana Marulanda, Zenghui Wu, Reggie Hamdy, Sena Tavukcu, Noémi Dahan‐Oliel, Frank Rauch   +7 more
wiley   +1 more source

Associations of muscle strength and functional power with longitudinal change in HR-pQCT bone parameters: the Osteoporotic Fractures in Men (MrOS) Study. [PDF]

J Bone Miner Res
Heilmann NZ, Freeland KS, Yu T, Caserotti P, Burghardt AJ, Knueven MW, Nindl BC, Ruppert KM, Stefanick ML, Bouxsein ML, Lane NE, Cauley JA, Strotmeyer ES.   +12 more
europepmc   +1 more source