Advanced Science, EarlyView.A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li +9 more
wiley +1 more source
Bone Mineral Density in Dual Energy X-Ray Absorptiometry and Hounsfield Units on Diagnostic Computed Tomography Scan: A Cross-Sectional Study. [PDF]
J Bone MetabPark WR, Kwon YJ, Lee DH.
europepmc +1 more source
Advanced Science, EarlyView.An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu +10 more
wiley +1 more source
Bioavailability and growth performance of zinc sulfate, zinc glycinate, zinc amino acid hydrate, and zinc methionine hydroxy analog in male broilers. [PDF]
Poult SciMortada M +7 more
europepmc +1 more source
Advanced Science, EarlyView.MI/RI is a major clinical challenge with high morbidity and mortality. This study demonstrates that SR‐A3 expression is downregulated in MI/RI, and its deletion exacerbates damage via the USP18/ISG15/STING axis, revealing SR‐A3 as a potential therapeutic target.
Yufei Han +24 more
wiley +1 more source
Bone Health in Breast Cancer Patients: Comparative Evaluation Using Dual Energy X-Ray Absorptiometry Scan and High-Resolution Peripheral Quantitative Computed Tomography. [PDF]
J Bone MetabKumari S +6 more
europepmc +1 more source
Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments
Advanced Science, EarlyView.Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang +10 more
wiley +1 more source
Understanding the influence of geometry and material properties on femoral and tibial stress and strain analysis in a paediatric population for single-leg standing simulation. [PDF]
Front Bioeng BiotechnolKämpf S, Xu Y, Choisne J.
europepmc +1 more source
TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis
Advanced Science, EarlyView.A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu +12 more
wiley +1 more source
Outcomes of Megaprosthetic Reconstruction After Tumor Resection of the Distal Femur and Proximal Tibia: A Single-Center Retrospective Study of 241 Cases. [PDF]
J Clin MedAyhan B +4 more
europepmc +1 more source