Results 91 to 100 of about 139,581 (225)

CÉLULAS-TRONCO MESENQUIMAIS ALÓGENAS DERIVADAS DE TECIDO ADIPOSO NAS OSTEOSSÍNTESES MINIMAMENTE INVASIVAS NA TÍBIA DE CÃES

, 2017
O tratamento das fraturas, especialmente aquelas causadas por traumas de alta energia, permanece como grande desafio aos cirurgiões médicos e veterinários.
Mallard, Patricia, Franco, Guilherme Galhardo, Pereira, Nicole Wolski, Watanabe Minto, Bruno, Filgueira, Fabricia Geovânia Fernandes, Dias, Luis Gustavo gosuen Gonçalves   +5 more
core   +1 more source

Versatile Co‐Engineering of Immunogenic Cell Death‐Primed Dead Tumor Cell Bodies With Tumor‐Activated MnO2 for cGAS‐STING‐Potentiated Personalized Immunotherapy

Advanced Science, EarlyView.
DTBEI@CS@MnO2, fabricated via modular electrostatic co‐engineering and photothermal/photodynamic immunogenic cell death, specifically responds to the acidic and GSH‐rich tumor microenvironment. This triggers the release of DTBEI that provides tumor antigens, DNA, and DAMPs, as well as the generation of Mn2+, thereby synergistically potentiating cGAS ...
Bolun Xu, Xuan Lu, Yuquan Wang, Haihua Ji, Ying Zhang, Yiqun Wan, Hao Wan   +6 more
wiley   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Iron‐Tannic Acid Hydrogel Mediated Mild Photothermal Therapy Combined With Ferroptosis Enhances Anti‐Tumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu, Xi Yu, Tao Wang, Wanyi Liu, Chang Lu, Jiani Zhong, Yujie He, Wei Li, Kunxi Zhang, Peihao Yin, Zeting Yuan   +10 more
wiley   +1 more source

Propriedades mecânicas do ligamento cruzado anterior em modelo porcino. [PDF]

, 2007
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Costa, Rafael Brehm da
core  

SR‐A3 Promotes USP18‐Mediated deISGylation of STING to Protect Against Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
MI/RI is a major clinical challenge with high morbidity and mortality. This study demonstrates that SR‐A3 expression is downregulated in MI/RI, and its deletion exacerbates damage via the USP18/ISG15/STING axis, revealing SR‐A3 as a potential therapeutic target.
Yufei Han, Guolin Miao, Yinqi Zhao, Zhiyong Du, Kaikai Lu, Changqi Xiao, Aiden Xian, Jiaxin Duanmu, Zihao Zhou, Jinxuan Chen, Lianxin Zhang, Chao Zhai, Yitong Xu, Zhaoling Li, Xianqin Shen, Sijing Shi, Jingxuan Chen, Si Mei, Yuan Fang, Liwen Zheng, Ling Zhang, Yuhui Wang, Wei Huang, Erdan Dong, Xunde Xian   +24 more
wiley   +1 more source

The Utility and Limitations of the Transfibular Approach in Ankle Trauma Surgery

Case Reports in Orthopedics, 2014
The commonly used extensive approaches to the distal tibia include the posteromedial and anterolateral approaches. The current report describes several cases performed using this technique establishing a rationale and safe zone for performing a ...
Mustafa Yassin, Avraham Garti, Muhammad Khatib, Moshe Weisbrot, Uzi Ashkenazi, Edward Ram, Dror Robinson   +6 more
doaj   +1 more source

Revisió dels resultats de les fractures diafisàries de tíbia

, 2021
Estudi d'avaluació dels resultats del tractament de fractures diafisàries de tíbia mitjançant la tècnica quirúrgica d'enclavat endomedul·lar fresat i bloquejat, amb un seguiment mig de 14 mesos.
Calbet i Montcusí, Gisela, García Almagro, Eugenio, Universitat Autònoma de Barcelona. Facultat de Medicina, Mir Bulló, Francesc Xavier, Universitat Autònoma de Barcelona. Departament de Cirurgia   +4 more
core  

Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments

Advanced Science, EarlyView.
Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang, Pan Liu, Jie Lei, Shuchang Peng, Qiu Chen, Wei Guan, Yizhou Zhu, Gang Liu, Xiaobo Feng, Cao Yang, Lei Tan   +10 more
wiley   +1 more source

Osteossíntese distal de tíbia por transfixação tíbio-tarsal em pequenos animais

, 1999
Neste experimento foram utilizados 15 animais, 11 caninos e 4 felinos, portadores de fratura distal de tíbia, tratados pela imobilização tíbio-tarsal com um fixador externo.
Alievi Marcelo Meller, Teixeira Marcelo Weinstein, Schossler João Eduardo   +2 more
core