Results 101 to 110 of about 140,566 (249)

Una aproximació a l’explotació dels recursos faunístics a Menorca durant l’edat del Bronze: la naveta de cala Blanca (Ciutadella) [PDF]

, 2012
This paper proposes a first approach to the knowledge of the domestic exploitation of animal resources by the Menorcan inhabitants of the Bronze Age, which is made through the study of the faunal assemblage recovered in the dwelling naveta of Cala Blanca.
Anglada, Montserrat, Ramis, Damià
core  

An Implantable Scaffold Sequentially Releasing STING Agonist and B7‐H3 Antibody for Bone Metastasis Immunotherapy

Advanced Science, EarlyView.
We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin, Hong Xiao, Shuai Fan, Kaimin Cai, Yanteng Xu, Xinwen Wang, Guanhong Chen, Chuandong Lang, Xinsheng Peng, Mingqiang Li, Yuhu Dai   +10 more
wiley   +1 more source

Posterior cruciate ligament's tibial insertions: topographic anatomy and morphometric study

Revista Brasileira de Ortopedia, 2013
OBJECTIVE: To provide anatomical and morphometric basis of the posterior cruciate ligament's tibial insertions in order to assist the creation of anatomical tibial tunnels, in the ligament surgical reconstruction.
Julio Cesar Gali, Hector Campora de Sousa Oliveira, Bruno Cesar Bracher Lisboa, Bruno DiSerio Dias, Fabiana de Godoy Casimiro, Edie Benedito Caetano   +5 more
doaj   +1 more source

Estudi de les restes de fauna del jaciment de Forat de Conqueta (Santa Linya, Lleida) [PDF]

, 2011
El text presenta els resultats de l'estudi de les restes de fauna del jaciment de Forat de Conqueta. El conjunt està integrat per restes d'animals domèstics i abundant microfauna.
Martínez Moreno, Jorge, Samper Carro, Sofia Cristina   +1 more
core   +2 more sources

Neutrophil‐Driven Cascade‐Targeted Nanocarriers Restore Mitochondrial Homeostasis to Ameliorate Renal Ischemia–Reperfusion Injury

Advanced Science, EarlyView.
A neutrophil‐mediated dual‐targeting liposome (NKN‐LNP) is developed to treat renal ischemia–reperfusion injury. The system enables spatiotemporally controlled delivery of NMN to injured tubules via MMP‐2/9 activation and KIM1 recognition, restoring mitochondrial function through NAD+‐SIRT3 signaling and preventing the transition from acute kidney ...
Hangbin Ma, Yang Li, Shen Lin, Feifan Chu, Gaozhan Ren, Yinhui Mao, Mingzhi Wu, Yuning Ma, Qiwei Ji, Zujie Chen, Jinzhong Ji, Mingxin Sun, Yongpeng Xu, Xiaoli Sun, Longguang Tang, Hao Zhou   +15 more
wiley   +1 more source

Osteossíntese de tíbia e fíbula em cão adulto

Pubvet
A fratura de tíbia e fíbula em cães geralmente é causada por atropelamentos, sendo uma lesão comum e grave. Os principais sinais clínicos incluem dor intensa, inchaço, deformidade e incapacidade de apoiar o membro afetado.
Bárbara Ferreira, Gerard Andrade de Araújo Araújo, Gustavo Henrique Silva Santos, Luiz Gustavo Macena de Avelar, Maria Larissa Rodrigues de Almeida, Pedro Lucas Rocha Pereira   +5 more
doaj   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

Advanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu, Yaqian Cui, Yongqiang Zhou, Yihui Zheng, Lijiang Huang, Leiming Jin, Qianhui Zhang, Pan Chen, Mengsha Lin, Jiaxi Ye, Yongqiang Xiong, Joo Young Huh, Xiang Hu, Xiaokun Li, Wu Luo, Guang Liang   +15 more
wiley   +1 more source

The Utility and Limitations of the Transfibular Approach in Ankle Trauma Surgery

Case Reports in Orthopedics, 2014
The commonly used extensive approaches to the distal tibia include the posteromedial and anterolateral approaches. The current report describes several cases performed using this technique establishing a rationale and safe zone for performing a ...
Mustafa Yassin, Avraham Garti, Muhammad Khatib, Moshe Weisbrot, Uzi Ashkenazi, Edward Ram, Dror Robinson   +6 more
doaj   +1 more source

Bone grafts and substitutes in small animal orthopaedic reconstrutive surgery: a breaf review [PDF]

, 2013
We present here an overview of the scientific literature concerning the clinical application of autografts and allografts of the skeletal tissues and of the natural and synthetic bone graft substitutes available in small animal orthopedic surgery for ...
Azevedo, Jorge T., Carvalho, Pedro Miguel Pires de, Dias, Isabel R., Lempeck, Marthin Raboch, Sousa, Cristina Maria Peixoto de, Viegas, Carlos A.   +5 more
core  

Cryoablation Activates the cGAS–STING‐CXCL10 Axis in Macrophages to Enhance Anti‐Tumor Immunity in NSCLC

Advanced Science, EarlyView.
Tumor dsDNA released by cryoablation is taken up by macrophages, activating the cGAS‐STING signaling pathway. This leads to an expansion of the CXCL10+ macrophage pool and increased secretion of CXCL10, which in turn recruits CXCR3+ T cells from draining lymph nodes into the tumor microenvironment to exert anti‐tumor effects.
Xinxin Zhi, Zhengcao Xing, Libo Luo, Jiale Wang, Xinyu Liu, Jia Yu, Jizhong Yin, Bin Chen, Yiwei Liu, Hui Sun, Guanghui Gao, Lei Wang, Xiaoxia Chen, Fei Li, Hu Ma, Lin Wang, Shuo Yang, Shengxiang Ren   +17 more
wiley   +1 more source