Results 81 to 90 of about 139,581 (225)

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

open access: yesAdvanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao   +7 more
wiley   +1 more source

Posterior cruciate ligament's tibial insertions: topographic anatomy and morphometric study

open access: yesRevista Brasileira de Ortopedia, 2013
OBJECTIVE: To provide anatomical and morphometric basis of the posterior cruciate ligament's tibial insertions in order to assist the creation of anatomical tibial tunnels, in the ligament surgical reconstruction.
Julio Cesar Gali   +5 more
doaj   +1 more source

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

open access: yesAdvanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang   +7 more
wiley   +1 more source

Estudo experimental do efeito das hastes femorais na tíbia RATJ [PDF]

open access: yes, 2008
Mestrado em Engenharia MecânicaEste trabalho visa avaliar o uso das hastes no fémur quando existem defeitos ósseos significativos neste que possam influenciar o comportamento biomecânico da tíbia.
Rego, Ana Maria Moreira Amorim de
core  

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

open access: yesAdvanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su   +14 more
wiley   +1 more source

Osteossíntese de tíbia e fíbula em cão adulto

open access: yesPubvet
A fratura de tíbia e fíbula em cães geralmente é causada por atropelamentos, sendo uma lesão comum e grave. Os principais sinais clínicos incluem dor intensa, inchaço, deformidade e incapacidade de apoiar o membro afetado.
Bárbara Ferreira   +5 more
doaj   +1 more source

Radiographic Assessment of the Safe Zone for Medial Oblique Opening Wedge High Tibial Osteotomy

open access: yesJournal of Orthopaedic Surgery, 2012
Purpose. To compare different cephalocaudal angles of the X-ray beam in measuring internal rotation of the proximal tibia that best demonstrates the safe zone. Methods. 10 pairs of embalmed, disarticulated knee joints from 10 cadavers were used.
Thana Siripisitsak   +3 more
doaj   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

open access: yesAdvanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan   +6 more
wiley   +1 more source

TRATAMENTO DE MÁ UNIÃO DE TÍBIA EM TAMANDUÁ-BANDEIRA (Myrmecophaga tridactyla)

open access: yes, 2019
A destruição do habitat natural vem forçando a ocupação de ambientes periurbanos/urbanos, o que juntamente com a grande extensão de rodovias que cruzam nossos biomas, levam ao aumento progressivo de traumas automobilísticos potencialmente nocivos.
Magalhães, Tryssia Scalon
core   +1 more source

PROTAC‐Engineered Protein/DNA Nanoantigen is a Potent Booster for Dendritic Cell Vaccines in Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A PROTAC‐functionalized protein/DNA‐integrated nanoantigen platform is developed to enhance dendritic cell vaccine potency. By combining a VHL‐recruiting peptide‐modified antigen with a sustained expression plasmid within CaCO3 nanoparticles, this system amplifies cross‐presentation, promotes DC maturation, and elicits robust Th1 and CTL responses ...
Peng Liu   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy