Results 71 to 80 of about 139,581 (225)

Differential Tissue‐Coupled Powering for Battery‐Free Injectable Electroceuticals

Advanced Science, EarlyView.
A thread‐like injectable neural stimulator is powered through differential tissue‐coupled powering (DTCP), which harvests RF‐frequency tissue potentials with an elongated receiver while preserving a injectable cross‐section. The system integrates an ASIC, stimulation electrodes, and a portable transmitter, enabling wireless peripheral nerve stimulation,
Han Wu, Sultan Mahmud, Mali Halac, Asif Iftekhar Omi, Domenica Sofia Baez Rodas, Jeremiasz Dados, Chaojun Cheng, Anyu Jiang, Cameron Wallace, Anvi Singh, Erin Patrick, Baibhab Chatterjee, Shriya Srinivasan, Adam Khalifa   +13 more
wiley   +1 more source

Adaptações biomecânicas do osso cortical de camundongos submetidos à três diferentes modalidades de exercício [PDF]

Acta Ortopédica Brasileira, 2013
OBJETIVO: Comparar os efeitos adaptativos de três modalidades de exercício de impacto reduzido nas adaptações mecânicas do osso cortical. MÉTODOS: Vinte e quatro camundongos machos, espécie Balb/c (25±3g), foram divididos aleatoriamente em quatro grupos (
Fernando Tadeu Trevisan Frajacomo, Maurício José Falcai, Cleverson Rodrigues Fernandes, Antonio Carlos Shimano, Sérgio Britto Garcia   +4 more
doaj   +2 more sources

Causas da síndrome do estresse medial da tíbia em corredores de rua: uma revisão de literatura [PDF]

, 2011
O presente estudo teve como objetivo avaliar as causas da síndrome do estresse medial da tíbia (SEMT) em corredores de rua. A SEMT é definida como dor ao longo da borda póstero medial da tíbia que ocorre durante o exercício.
Denise Alves Gomes
core  

Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation

Advanced Science, EarlyView.
Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang, Wenhui Xie, Lei Yang, Zhengrong Wang, Yi Huang, Peng Huang, Yuan Liu, Jun Hu   +7 more
wiley   +1 more source

Loss of SHP1 in Spinal Astrocytes Triggers T‐Lymphocyte Infiltration and Nociceptive Hypersensitivity

Advanced Science, EarlyView.
Astrocyte‐specific SHP1 deletion disrupts astrocyte–vascular interactions and compromises BBB integrity while enhancing STAT1‐dependent CXCL10 expression. These changes synergistically promote peripheral CD4+ and CD8+ T‐cell infiltration into the SDH. The infiltrating T cells secrete IFN‐γ, which in turn activates microglia.
Lan‐Xing Yi, Lin Yang, Kang‐Li Wang, Hui‐Zhu Liu, Rui‐Ying Chen, Min Su, Xiao Xiao, Yu‐Qiu Zhang   +7 more
wiley   +1 more source

EXPERIMENT AND SIMULATION ON MECHANICAL PROPERTIES OF OSTEOPOROTIC MOUSE BONE (MT)

Jixie qiangdu, 2023
The osteoporosis model of mouse tibia was established based on castration, and the effect of osteoporosis on the mechanical properties of tibia was investigated. The two-dimensional sections of mouse tibia were obtained by Micro-CT. The three-dimensional
ZHAO Qing, YIN ZiYang, ZHOU Wen, REN GuanLin, KUANG ChunMei, HU Cong, ZHOU ChangJiang   +6 more
doaj  

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source

Osteossíntese de fêmur e tíbia em veado-catingueiro (Mazama gouazoubira): relato de caso

, 2018
RESUMO O presente estudo relata o caso de um veado-catingueiro jovem, provindo de vida livre e com histórico de atropelamento. Posteriormente à realização de exames, o animal foi diagnosticado com fratura exposta distal de tíbia (Salter-Harris tipo I) e ...
E.A.R. Santos, Surita,L.E., L.E. Surita, M.M. Alievi, Alievi,M.M., Santos,E.A.R., B. Zafalon-Silva, Zafalon-Silva,B.   +7 more
core   +2 more sources

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

Tratamento de osteonecrose da tíbia induzida por corticosteroides – descompressão e Haste intramedular de tíbia - relato de caso

Journal of the Foot & Ankle
A osteonecrose associada ao uso de corticosteroides é a segunda causa mais frequente de osteonecrose não traumática. A maioria das evidências concentra-se na cabeça femoral, havendo escassez de dados sobre acometimento metadiafisário e sobre estratégias
Tânia Szejnfeld Mann
doaj   +1 more source