Results 21 to 30 of about 21,024 (161)

Hybrid Probiotic Hydrogel With Curcumin‐Loaded MnO2 Nanoparticles Enhances Diabetic Wound Healing Through Multimodal Microenvironmental Regulation

open access: yesRare Metals, EarlyView.
ABSTRACT Skin wound injuries are often accompanied by bacterial infections and severe inflammation. Especially, M1‐type macrophages at the wound site can trigger a cascade of inflammatory responses, mediating a vicious cycle of inflammation. Meanwhile, hypoxia further exacerbates vascular damage and constriction in the wound microenvironment, thereby ...
Xianfeng Wang   +6 more
wiley   +1 more source

Engineering a Tumor‐Targeted MgH2@Lip/PD‐L1 Nanoplatform for Synergistic Hydrogen Therapy and Immune Activation

open access: yesRare Metals, EarlyView.
ABSTRACT Lung cancer remains the leading cause of cancer‐related deaths worldwide, yet immune checkpoint blockade (ICB) is often compromised by an immunosuppressive tumor microenvironment (TME) with acidosis, hypoxia, and poor T cell infiltration. Here, we develop a TME‐responsive nanoplatform (MgH2@Lip/PD‐L1) that couples hydrogen gas therapy with PD ...
Xuyu Gu   +5 more
wiley   +1 more source

Elevation, soil pH and calcium availability shape regional and local scale spatial patterns of PhoD gene abundance in tropical and subtropical forests

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Organic phosphorus mineralization is a critical process in the phosphorus cycle, governing phosphorus bioavailability for plants. The PhoD gene, which encodes the key enzyme alkaline phosphatase, serves as a valuable biomarker for this process.
Sandhya Mishra   +3 more
wiley   +1 more source

Use of a Cytobrush for Sampling the Ear Canal of Dogs With Otitis Externa

open access: yesVeterinary Dermatology, EarlyView.
Cytological examination of the ear canal is essential for evaluating dogs with otitis externa (OE). The conventional sampling method uses a swab. However, the cytobrush (gynaecological cervical brush), already used for cytological collection from other anatomical sites, has not been adequately investigated for this purpose in dogs with OE.
Nicoly Radaeli Atanasio   +3 more
wiley   +1 more source

Efficacy of Der f 2/Zen 1‐LAMP1 Plasmid‐Based Vaccine Immunotherapy in Dogs With Atopic Dermatitis: A Proof‐of‐Concept Study

open access: yesVeterinary Dermatology, EarlyView.
Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Petra Bizikova   +6 more
wiley   +1 more source

Assessing D‐Squame as a Minimally Invasive Technique to Evaluate the Cutaneous Immune Response mRNA in a Dog Model of Canine Atopic Dermatitis

open access: yesVeterinary Dermatology, EarlyView.
ABSTRACT Background Canine atopic dermatitis (cAD) is a multifactorial, inherited skin disease, estimated to affect ≤ 15% of dogs. Studies of skin messenger mRNA in cAD currently use invasive methods, including blood sampling and biopsy collection, whilst advances in human atopic dermatitis study methodology have demonstrated reliable use of minimally ...
Xavier Langon   +5 more
wiley   +1 more source

Single Cold Atmospheric Plasma Therapy May Improve the Treatment Outcome of Canine Otitis Externa With Secondary Infection

open access: yesVeterinary Dermatology, Volume 37, Issue 1, Page 103-110, February 2026.
Background: Otitis externa with secondary bacterial or yeast infection is a common problem in small animal practice. Cold physical plasma (CPP) has been reported to have antimicrobial activity in vitro. Results: Ears treated additionally with CPP showed lower otic scores after 21 days compared to nontreated ears, although this difference was not ...
Ralf S. Mueller, Cosima Bouassiba
wiley   +1 more source

Injectable Biomimetic Composite Hydrogel Scaffold With Tissue‐Engineered Cartilage Matrix for Articular Cartilage Regeneration

open access: yesRare Metals, Volume 45, Issue 1, January 2026.
ABSTRACT Articular cartilage regeneration remains a significant challenge because of its limited intrinsic healing capacity and the inadequacy of conventional treatments for restoring structural and functional integrity. In this study, a novel injectable composite hydrogel scaffold was designed to mimic the extracellular matrix (ECM) of native ...
Zhong‐Lian Wu   +13 more
wiley   +1 more source

Endogenous/Exogenous Dual‐Responsive Bimetallic Hollow Nanozyme for Photothermal/Nanocatalysis/Immune Synergistic Tumor Therapy

open access: yesRare Metals, Volume 45, Issue 1, January 2026.
ABSTRACT Nanozymes have attracted considerable attention in cancer therapy due to their adjustable enzyme activity and high catalytic efficiency. However, they still face a major challenge from tumor metastasis. In this work, endogenous/exogenous dual‐responsive bimetallic hollow PdRu (termed HPdRu) nanozymes were prepared.
Nan‐Nan Zheng, Xin Hu, Jun‐Qing Hu
wiley   +1 more source

Boron Difluoride Chelated Aminoanthraquinone Photosensitizer for Type I Photodynamic Therapy

open access: yesRare Metals, Volume 45, Issue 1, January 2026.
ABSTRACT Type I photosensitizers capable of generating cytotoxic reactive oxygen species (ROS), with reduced oxygen dependence under photoirradiation, are regarded as a promising phototherapeutic approach for hypoxic solid tumors. Herein, based on the electron donor of 9‐phenyl‐carbazole (Cz) and the electron acceptor of anthraquinone (AQ ...
Tian Zhang   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy