Results 31 to 40 of about 13,733 (166)
Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 3, Page 272-282, March 2026.ABSTRACT Objective Complete hydatidiform mole and coexisting normal fetus (CHMCF) is a rare condition for which there is significant heterogeneity in diagnosis, counseling and management of complications. The objective of this study was to summarize the prevalence of clinical outcomes in reported cases of CHMCF.
N. Salmeri +8 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2013 肺癌是严重威胁人类生命健康的常见恶性肿瘤,它的发生、进展和转移等与机体的细胞免疫机能密切相关。细胞免疫是机体抗肿瘤免疫的重要机制,细胞免疫应答主要是T细胞介导的特异性细胞免疫[1]。T淋巴细胞是机体免疫系统内功能最重要的一大细胞群,同时又是一个复杂的细胞群体。T细胞和NK细胞在免疫监视、杀伤靶细胞及免疫调节方面具有极其重要的作用。正常情况下,T细胞及亚群的数目处于相对平衡状态,免疫功能稳定。若T细胞总数或者CD4+/CD8 ...
任林广 +4 more
doaj
Treatment of refractory severe dry eye with 0.1% tacrolimus eyedrops [PDF]
, 2016 目的：评估0.1%他克莫司滴眼液治疗难治性重度干眼疗效。 方法：本研究招募已使用人工泪液合并激素治疗半年或半年以上，但干眼症状及体征未见明显缓解的重度干眼患者26名。所有给予0.1%他克莫司滴眼液合并人工泪液治疗，并于治疗前、治疗后1月、2月及3月观察干眼相关临床指标，包括：干眼症状评分(OcularSurfaceDiseaseIndex，OSDI)、泪膜破裂时间(Tearbreakuptime，TBUT)、泪液分泌试验(SchirmerI)、角膜荧光素钠染色评分 ...
杨舒
core
Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 3, Page 376-384, March 2026.ABSTRACT Objective To investigate whether combining abnormal morphological features observed on ultrasound in live pregnancies that ended in a first‐trimester miscarriage can predict an abnormal karyotype. Methods This retrospective observational cohort study was conducted at the early‐pregnancy assessment unit at University College London Hospital ...
T. Setty +5 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2006 [目的]通过定量分析慢性乙型肝炎患者体内乙型肝炎病毒（HBV）特异性的细胞毒性T淋巴细胞,探讨特异性细胞毒性T淋巴细胞水平与血清丙氨酸氨基转移酶水平和病毒复制状态的关系.[方法]从慢性乙型肝炎患者外周血分离外周血单个核细胞（PBMC）,用HLA-A2限制的HBcAg抗原表位肽-五聚体复合体及CD8单克隆抗体染色后,用流式细胞仪检测HBV特异性的细胞毒性T淋巴细胞,同时检测患者的肝功能和定量分析HBV DNA.[结果]32例HLA-A2阳性的慢性乙型肝炎患者外周血均可检测到HBV特异性的细胞毒性T淋巴细胞,
邓洪 +6 more
doaj
HUVECs Promote the Proliferation of iPS-MSCs by FAM3B [PDF]
, 2016 间充质干细胞（mesenchymalstemcells，MSCs）存在于一个血管周微环境中，在这个微环境内，内皮细胞（endothelialcells，ECs）与MSCs互相作用，调控MSCs的表型和增殖，从而在MSCs的血管生成作用和治疗应用方面起重要作用。然而，MSCs受到来源、年龄、健康等多方面的影响，不能满足大规模的使用需求。诱导多能干细胞来源的间充质干细胞（inducedpluripotentstemcell-derivedMSCs，iPS-MSCs）可能会是一个有前景的替代性干细胞来源。但是，
冷云
core
Multi‐Functional S‐HA/ASTA NPs Coating on Biodegradable ZE21B Alloy for Cerebrovascular Applications
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Magnesium (Mg) and its alloys have attracted extensive attention of researchers in the field of cerebrovascular implants due to their good mechanical properties and biosafety. However, rapid degradation and delayed endothelialization pose challenges. To address these issues, this study introduces a multifunctional composite coating.
Aqeela Yasin +4 more
wiley +1 more source
中国HCV/HIV合并感染者T淋巴细胞表面CD81、CXCR3表达的研究
Zhongguo shiyan zhenduanxue, 2006 目的探讨T淋巴细胞表面受体CD81、CXCR3,在丙肝病毒（HCV）单纯感染,艾滋病病毒（HIV）单纯感染和HCV/HIV合并感染过程中的表达及意义。方法采用流式细胞术,检测HCV感染组（n=21）,HIV感染组（n=14）,HCV/HIV感染组（n=28）及正常对照组（n=30）人外周血CD4+T淋巴细胞和CD8+T淋巴细胞表面CD81、CXCR3的表达。结果HIV感染组及HCV/HIV合并感染组CD4+T细胞表面CD81、CXCR3表达显著降低 ...
康辉 +6 more
doaj
Recombinant IL-33 prolongs leflunomide-mediated graft survival through reducing Th1-type cytokine IFN-γ and expanding CD4+Foxp3+ regulatory T cells (Treg) in concordant heart transplantation [PDF]
, 2015 摘要 背景 白细胞介素33是一种非典型的IL-1家族成员。IL-33的给药与Th2型（Th2细胞）的应答促进相关联，其通过促进Th2细胞的活性和Th类型2相关的细胞因子，在体内，特别是以IL-4和IL-5的增殖为代表。最近，在同种异体心脏移植，IL-33显示出其能增加小鼠体内的CD4+Foxp3+调节性T细胞（Treg细胞），并抑制Th1型相关细胞因子IFN-γ的水平。我们采用小鼠到大鼠协调性异种移植模型，我们推测，IL-33和来氟米特可以延长移植物的存活。在这个模型中 ...
代辰
core
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Intervertebral disc degeneration (IDD) is a predominant cause of low back pain, significantly impacting quality of life. Mitochondrial fitness is essential in the progression of IDD, as it regulates cellular senescence and pyroptosis. This study investigates the role of mitochondrial caseinolytic protease P (ClpP) in alleviating senescence and
Kun Wang +7 more
wiley +1 more source