Results 31 to 40 of about 13,640 (166)
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT The limited osteogenic capacity of magnesium phosphate cement (MPC) has constrained its biomedical applications, underscoring the necessity to develop MPC with enhanced physical properties and bone‐forming capabilities. In this study, a multifunctional MPC system was developed by incorporating zoledronic acid‐loaded near‐infrared (NIR ...
Bin Wang +8 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2019 目的探究外周血T淋巴细胞亚群在不同致敏原因哮喘儿童中的表达,旨在为临床的诊断和治疗提供科学依据。方法选取2016年4月至2018年4月于我院接受治疗的84例哮喘儿童为研究对象,根据致敏原因将所有患者分为两组,其中观察组为多重致敏,共43例患者,对照组为单一致敏,共41例,比较两组患者的CD4+细胞和CD8+细胞及两者的比值、Th1细胞和Th2细胞及两者的比值、Tregs细胞和Th17细胞及两者的比值。结果观察组患者的CD4+细胞高于对照组患者,CD8+T细胞低于对照组患者,且两者比值更大 ...
曾建兴 +5 more
doaj
The Effect C-X-C Motif Chemokine 10 Exert to Acute Rejection in Rat Allogenic Cardiac Retransplantation Model [PDF]
, 2016 目的 γ干扰素诱导的蛋白10(IP-10/CXCL10)在器官初次移植排斥反应中起着重要作用，但其在再次移植中的作用仍不明确，本文主要研究趋化因子CXCL10是否能够对再次移植急性排斥反应的产生影响；由于记忆性T细胞的存在，心脏再次移植排斥反应对传统免疫抑制剂不敏感，因此，在再次移植基础上应用特异性CXCL10抗体来观察其是否能够减轻再次移植物炎症细胞浸润，延长心脏再次移植的存活时间。 方法 实验一、对照组（HTx）：仅接受一次腹腔异位心脏移植；实验组（HRTx ...
许佳承
core
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT This study introduces novel nonequiatomic TiZrCoCrMoCux (x = 0, 5, 10; at%) medium‐entropy alloys (MEAx) tailored for orthopedic implants, synergistically combining the biocompatibility of Ti‐based alloys, the wear resistance of CoCrMo alloys, and the antibacterial/osteogenic attributes of Cu. The alloy's microstructure, mechanical properties,
Hang Yu +9 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2006 [目的]通过定量分析慢性乙型肝炎患者体内乙型肝炎病毒（HBV）特异性的细胞毒性T淋巴细胞,探讨特异性细胞毒性T淋巴细胞水平与血清丙氨酸氨基转移酶水平和病毒复制状态的关系.[方法]从慢性乙型肝炎患者外周血分离外周血单个核细胞（PBMC）,用HLA-A2限制的HBcAg抗原表位肽-五聚体复合体及CD8单克隆抗体染色后,用流式细胞仪检测HBV特异性的细胞毒性T淋巴细胞,同时检测患者的肝功能和定量分析HBV DNA.[结果]32例HLA-A2阳性的慢性乙型肝炎患者外周血均可检测到HBV特异性的细胞毒性T淋巴细胞,
邓洪 +6 more
doaj
Mechanistically Investigation for The Significance of Secreted Proteins in Diagnosis of Breast Cancer [PDF]
, 2016 分泌蛋白对于乳腺癌的发生、发展起着至关重要的作用。有研究表明，分泌蛋白协同作用可促进正常乳腺细胞在软琼脂上的生长，结果提示多个分泌蛋白水平的变化可能是乳腺癌发生、恶化的标志。本研究拟利用乳腺癌临床血液样本，分析血清中几种分泌蛋白的含量，探讨几种分泌蛋白联用在乳腺癌诊断中的意义，并进一步研究这些分泌蛋白在促进乳腺癌细胞迁移、侵袭过程中的作用。 本文首先用ELISA双抗体夹心方法检测临床血清样本中IL6、IL9、IL21、FGF1、FGF10、FGF14的含量，结果表明IL6，FGF1 ...
胡修永
core
Veterinary Dermatology, Volume 37, Issue 1, Page 103-110, February 2026.Background: Otitis externa with secondary bacterial or yeast infection is a common problem in small animal practice. Cold physical plasma (CPP) has been reported to have antimicrobial activity in vitro. Results: Ears treated additionally with CPP showed lower otic scores after 21 days compared to nontreated ears, although this difference was not ...
Ralf S. Mueller, Cosima Bouassiba
wiley +1 more source
中国HCV/HIV合并感染者T淋巴细胞表面CD81、CXCR3表达的研究
Zhongguo shiyan zhenduanxue, 2006 目的探讨T淋巴细胞表面受体CD81、CXCR3,在丙肝病毒（HCV）单纯感染,艾滋病病毒（HIV）单纯感染和HCV/HIV合并感染过程中的表达及意义。方法采用流式细胞术,检测HCV感染组（n=21）,HIV感染组（n=14）,HCV/HIV感染组（n=28）及正常对照组（n=30）人外周血CD4+T淋巴细胞和CD8+T淋巴细胞表面CD81、CXCR3的表达。结果HIV感染组及HCV/HIV合并感染组CD4+T细胞表面CD81、CXCR3表达显著降低 ...
康辉 +6 more
doaj
Protein Kinase D3 Is Essential for Prostratin-stimulated Integrated HIV-1 Transcription activation via NF- κB Signaling Pathway [PDF]
, 2016 Prostratin，一种非肿瘤促进性的佛波酯，能够通过激活HIV-1病毒转录来清除潜伏期的HIV-1病毒，但其分子机制还不是很清楚。本文，我们发现PKD3对于Prostratin激活HIV-1病毒转录是必需的。 首先，敲除PKD3能够阻断Prostratin对HIV-1病毒的转录激活，而敲除PKD家族的其他成员则不能。而且过表达持续活性的PKD3，而非野生型或没有催化活性的PKD3，能增强HIV-1病毒转录水平。于此同时 ...
胡向明
core
Rare Metals, Volume 45, Issue 1, January 2026.ABSTRACT Articular cartilage regeneration remains a significant challenge because of its limited intrinsic healing capacity and the inadequacy of conventional treatments for restoring structural and functional integrity. In this study, a novel injectable composite hydrogel scaffold was designed to mimic the extracellular matrix (ECM) of native ...
Zhong‐Lian Wu +13 more
wiley +1 more source