Results 141 to 150 of about 407,843 (257)

Proanthocyanidins Alleviate T-2 Toxin-Induced Toxicity in Yak (<i>Bos grunniens</i>) Sertoli Cells by Alleviating Oxidative Stress and Modulating Mitochondrial Biogenesis. [PDF]

Antioxidants (Basel)
Zhang H, Liu D, Ding L, Zhang F, Mao J, He W, Zhuoma Q, He H, Fu W, Lan D, Yin S.   +10 more
europepmc   +1 more source

Evaluation of Effectiveness of a Novel Multicomponent Mycotoxins Detoxification Agent in the Presence of AFB1 and T-2 Toxin on Broiler Chicks. [PDF]

Microorganisms, 2023
Stefanović D, Marinković D, Trailović S, Vasiljević M, Farkaš H, Raj J, Tolimir N, Radulović S, Nešić V, Trailović JN, Petrujkić B.   +10 more
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Role of T-2 toxin in the modulation of oxidative homeostasis and immune function in three-dimensional hepatic cell cultures of chicken origin. [PDF]

Front Vet Sci
Vörösházi J, Mackei M, Sebők C, Tráj P, Márton RA, Neogrády Z, Mátis G.   +6 more
europepmc   +1 more source

Unraveling the Nrf2-ARE Signaling Pathway in the DF-1 Chicken Fibroblast Cell Line: Insights into T-2 Toxin-Induced Oxidative Stress Regulation. [PDF]

Toxins (Basel), 2023
Gao S, Wang K, Xiong K, Xiao S, Wu C, Zhou M, Li L, Yuan G, Jiang L, Xiong Q, Yang L, Yang L.   +11 more
europepmc   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Culture Condition-Dependent Acylation Patterns of Trichothecenes in a T-2 Toxin-Producing Strain of <i>Fusarium sporotrichioides</i> NBRC 9955. [PDF]

Int J Mol Sci
Maeda K, Tanaka Y, Nakajima Y, Matsui K, Koizumi Y, Ohsato S, Takahashi-Ando N, Kimura M.   +7 more
europepmc   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Structure-Based Design and Mechanistic Insight for Enhanced Catalytic Activity of Aldo/Keto Reductase AKR13B3 from <i>Devosia</i> A6-243 Toward T-2 Toxin. [PDF]

Toxins (Basel)
Liu J, Chi H, Zhu X, Jiang Q, Lu Z, Zhu P, Lu F.   +6 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source