Metabolism of HT-2 Toxin and T-2 Toxin in Oats [PDF]
Toxins, 2016 The Fusarium mycotoxins HT-2 toxin (HT2) and T-2 toxin (T2) are frequent contaminants in oats. These toxins, but also their plant metabolites, may contribute to toxicological effects. This work describes the use of 13C-assisted liquid chromatography–high-
Jacqueline Meng-Reiterer +5 more
doaj +3 more sources
Lycopene mitigates T-2 toxin-induced hepatic ferroptosis by targeting the Nrf2/mitophagy axis in mice [PDF]
npj Science of FoodT-2 toxin is a typical mycotoxin that seriously threatens human and animal health. Liver is the major target organ of T-2 toxin. To elucidate the precise hepatotoxicity mechanism and discover a natural antagonist of T-2 toxin.
Xu Yang +11 more
doaj +2 more sources
Fluorine impairs carboxylesterase 1-mediated hydrolysis of T-2 toxin and increases its chondrocyte toxicity [PDF]
Frontiers in Nutrition, 2022 BackgroundT-2 toxin is recognized as one of the high-risk environmental factors for etiology and pathogenesis of Kashin-Beck disease (KBD). Previous evidence indicates decreased serum fluorine level in KBD patients.
Yumeng Jia +10 more
doaj +2 more sources
T-2 toxin adsorption by hectorite [PDF]
Journal of the Serbian Chemical Society, 2009 The adsorption of T-2 toxin by the natural smectite mineral – hectorite at pH 3.0, 7.0 and 9.0 was investigated. The results of T-2 toxin adsorption on hectorite showed that the T-2 adsorption capacity decreased with increasing concentration of adsorbent
ALEKSANDRA DAKOVIĆ +5 more
doaj +4 more sources
Effects of T-2 toxin on growth performance, feather quality, tibia development and blood parameters in Yangzhou goslings [PDF]
Poultry Science, 2023 : T-2 toxin is a dangerous natural pollutant and widely exists in animal feed, often causing toxic damage to poultry, such as slow growth and development, immunosuppression, and death. Although geese are considered the most sensitive poultry to T-2 toxin,
Wang Gu +11 more
doaj +2 more sources
Peroxiredoxin 4 Ameliorates T-2 Toxin-Induced Growth Retardation in GH3 Cells by Inhibiting Oxidative Stress and Apoptosis [PDF]
MoleculesT-2 toxin, a highly toxic type A trichothecene, is a secondary fungal metabolite produced by various Fusarium species. The consumption of food and feed contaminated with T-2 toxin is a major factor contributing to growth retardation, posing significant ...
Qirong Lu +10 more
doaj +2 more sources
Effective protective agents against the organ toxicity of T-2 toxin and corresponding detoxification mechanisms: A narrative review [PDF]
Animal NutritionT-2 toxin is one of the most widespread and toxic fungal toxins in food and feed. It can cause gastrointestinal toxicity, hepatotoxicity, immunotoxicity, reproductive toxicity, neurotoxicity, and nephrotoxicity in humans and animals.
Pengju Wang +4 more
doaj +2 more sources
T-2 Toxin—The Most Toxic Trichothecene Mycotoxin: Metabolism, Toxicity, and Decontamination Strategies [PDF]
Molecules, 2021 Among trichothecenes, T-2 toxin is the most toxic fungal secondary metabolite produced by different Fusarium species. Moreover, T-2 is the most common cause of poisoning that results from the consumption of contaminated cereal-based food and feed ...
Edyta Janik +5 more
doaj +2 more sources
Tibial Damage Caused by T-2 Toxin in Goslings: Bone Dysplasia, Poor Bone Quality, Hindered Chondrocyte Differentiation, and Imbalanced Bone Metabolism [PDF]
AnimalsT-2 toxin, the most toxic type A trichothecene, is widely present in grain and animal feed, causing growth retardation and tissue damage in poultry. Geese are more sensitive to T-2 toxin than chickens and ducks.
Wang Gu +4 more
doaj +2 more sources
Investigation of the effects of T-2 toxin in chicken-derived three-dimensional hepatic cell cultures [PDF]
Scientific ReportsDespite being one of the most common contaminants of poultry feed, the molecular effects of T-2 toxin on the liver of the exposed animals are still not fully elucidated.
Júlia Vörösházi +8 more
doaj +2 more sources