Results 21 to 30 of about 921 (215)
Journal of Toxicologic Pathology, 2006 T-2 toxin is a cytotoxic fungal secondary metabolite produced by various species of Fusarium. This paper reviews the reported data about the development and/or mechanisms of T-2 toxin-induced apoptosis in the hematopoietic, lymphoid and gastrointestinal tissues, dorsal skin and fetal tissues of mice and rats.
Doi, Kunio +2 more
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Detection of T-2 toxin by an improved radioimmunoassay [PDF]
Applied and Environmental Microbiology, 1983 T-2 toxin in serum, urine, and saline was analyzed by a modified radioimmunoassay procedure. The specimens were added directly to the assay tubes without extraction steps. The reaction between antibody and ligands was optimal at 1 h. Albumin-coated charcoal was used to separate bound from free radioactivity.
P A, Fontelo +3 more
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miR449a/SIRT1/PGC-1α Is Necessary for Mitochondrial Biogenesis Induced by T-2 Toxin
Frontiers in Pharmacology, 2018 T-2 toxin is one of the type A trichothecenes produced mainly by the Fusarium genus. Due to its broad distribution and highly toxic nature, it is of great concern as a threat to human health and animal breeding.
Shijie Ma +8 more
doaj +1 more source
Survey for Fusaria That Elaborate T-2 Toxin [PDF]
Applied Microbiology, 1972 Of the 136 strains of Fusarium examined, T-2 toxin was confirmed by thinlayer chromatography in 13 of the 21 extracts that inhibited either Rhodotorula rubra or Pencillium digitatum .
H R, Burmeister +2 more
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Production of antibody against T-2 toxin [PDF]
Applied and Environmental Microbiology, 1979 Antibody against T-2 toxin was obtained after immunization of rabbits with bovine serum albumin-T-2 hemisuccinate conjugate. The antibody had greatest binding efficiency for T-2 toxin, less efficiency for HT-2, and least for T-2 triol. Cross-reaction of antibody with neosolaniol, T-2 tetraol, and 8-acetyl-neosolaniol was very weak.
F S, Chu +3 more
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Frontiers in Genetics, 2022 Many studies have shown that ingestion of the T-2 toxin is harmful to articular cartilage. However, the mechanisms underlying damaged articular cartilage induced by T-2 toxin have not been elucidated.
Longyan Shi +5 more
doaj +1 more source
Radioimmunoassay of T-2 Toxin in Corn and Wheat
Journal of AOAC INTERNATIONAL, 1981 Abstract A radioimmunoassay (RIA) for the determination of T-2 toxin in corn and wheat was developed. The toxin was first extracted with methanol, and the methanolic extract was washed with hexane and passed through a Sep-Pak C18 reverse phase cartridge.
S, Lee, F S, Chu
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The role of mitochondria in T-2 toxin-induced human chondrocytes apoptosis. [PDF]
PLoS ONE, 2014 T-2 toxin, a mycotoxin produced by Fusarium species, has been shown to cause diverse toxic effects in animals and is also a possible pathogenic factor of Kashin-Beck disease (KBD). The role of mitochondria in KBD is recognized in our recent research. The
Jiangtao Liu +7 more
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Autophagy and Apoptosis Interact to Modulate T-2 Toxin-Induced Toxicity in Liver Cells
Toxins, 2019 T-2 toxin is a mycotoxin generated by Fusarium species which has been shown to be highly toxic to human and animals. T-2 toxin induces apoptosis in various tissues/organs.
Jing Wu +6 more
doaj +1 more source
Evaluation of mycofix to ameliorate the toxic effect of t-2 toxin on performance of broiler chickens [PDF]
Iraqi Journal of Veterinary Sciences, 2007 The possible protective effect of Mycofix against the toxic effect of T-2 toxin in growing broiler chickens was investigated in two age stages; the first and second ages, ranged from 1-21 and 22-42 days, respectively.
A. M. Shareef, Z. A. Jameel
doaj +1 more source