Results 171 to 180 of about 11,020,373 (290)

Targeting Blimp-1 in T cells results in activation of T-bet-mediated control of immunosuppression in lung cancer. [PDF]

Cancer Immunol Immunother
Finotto S, Chiriac MT, Krammer S, Yang Z, Neurath L, Geppert CI, Nendel E, Trump S, Geiger A, Wirtz S, Zundler S, Neurath MF.   +11 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

T-bet-expressing Tr1 cells driven by dietary signals dominate the small intestinal immune landscape. [PDF]

Proc Natl Acad Sci U S A
Ansaldo E, Yong D, Carrillo N, McFadden T, Abid M, Corral D, Rivera C, Farley T, Bouladoux N, Gribonika I, Belkaid Y.   +10 more
europepmc   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

T-bet⁺ tissue-resident regulatory T cells are enriched in the neonatal mouse liver and promoted by IL-27 and IFN-γ. [PDF]

FEBS J
Yang L, Wang Y, Li M, Lian Z, Yin Z, Hao J, Sun X, Jin R, Ge Q.   +8 more
europepmc   +1 more source

T-bet-expressing B cells contribute to the autoreactive plasma cell pool in Lyn^-/- mice. [PDF]

Eur J Immunol, 2023
Ottens K, Schneider J, Satterthwaite AB.
europepmc   +1 more source

A role for T-bet in metabolic regulation [PDF]

Nature Reviews Immunology, 2013
openaire   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

A combination of proviral and antiviral roles of CD11c- and T-bet-expressing B cells defines parameters of chronic murine gammaherpesvirus infection. [PDF]

mBio
Johansen ER, Bradeen XG, Xie EV, Dittel BN, Leadbetter EA, Tarakanova VL.   +5 more
europepmc   +1 more source

Increased development of T-bet⁺CD11c⁺ B cells predisposes to lupus in females: Analysis in BXD2 mouse and genetic crosses. [PDF]

Clin Immunol, 2023
Sullivan KA, Chapman C, Lu L, Ashbrook DG, Wang Y, Alduraibi FK, Lu C, Sun CW, Liu S, Williams RW, Mountz JD, Hsu HC.   +11 more
europepmc   +1 more source