Results 21 to 30 of about 53,519 (232)

TREC mediated oncogenesis in human immature T lymphoid malignancies preferentially involves ZFP36L2

Molecular Cancer, 2023
The reintegration of excised signal joints resulting from human V(D)J recombination was described as a potent source of genomic instability in human lymphoid cancers.
Estelle Balducci, Thomas Steimlé, Charlotte Smith, Patrick Villarese, Mélanie Feroul, Dominique Payet-Bornet, Sophie Kaltenbach, Lucile Couronné, Ludovic Lhermitte, Aurore Touzart, Marie-Emilie Dourthe, Mathieu Simonin, André Baruchel, Hervé Dombret, Norbert Ifrah, Nicolas Boissel, Bertrand Nadel, Elizabeth Macintyre, Agata Cieslak, Vahid Asnafi   +19 more
doaj   +1 more source

Case Report: A Case With Philadelphia Chromosome Positive T-Cell Lymphoblastic Lymphoma and a Review of Literature

Frontiers in Oncology, 2021
Philadelphia chromosome positive (Ph+) in T-lineage acute lymphoproliferative tumors is a rare event in both children and adults. In particular, it has not been reported in T-cell lymphoblastic lymphoma(T-LBL) yet.
Xuewei Li, Xuewei Li, Nana Ping, Nana Ping, Yong Wang, Yong Wang, Xiaoyu Xu, Xiaoyu Xu, Lijuan Gao, Lijuan Gao, Zhao Zeng, Ling Zhang, Zhibo Zhang, Yiyu Xie, Changgeng Ruan, Changgeng Ruan, Changgeng Ruan, Depei Wu, Depei Wu, Depei Wu, Zhengming Jin, Zhengming Jin, Suning Chen, Suning Chen, Suning Chen   +24 more
doaj   +1 more source

Results and conclusions of the European Intergroup EURO-LB02 trial in children and adolescents with lymphoblastic lymphoma

Haematologica, 2017
In the European Intergroup EURO-LB02 trial, children and adolescents with lymphoblastic lymphoma underwent the non-Hodgkin lymphoma Berlin-Frankfurt-Münster protocol without prophylactic cranial radiotherapy.
Eva Landmann, Birgit Burkhardt, Martin Zimmermann, Ulrike Meyer, Wilhelm Woessmann, Wolfram Klapper, Grazyna Wrobel, Angelo Rosolen, Marta Pillon, Gabriele Escherich, Andishe Attarbaschi, Auke Beishuizen, Karin Mellgren, Robert Wynn, Richard Ratei, Adriana Plesa, Martin Schrappe, Alfred Reiter, Christophe Bergeron, Catherine Patte, Yves Bertrand   +20 more
doaj   +1 more source

FAS system deregulation in T-cell lymphoblastic lymphoma [PDF]

Cell Death & Disease, 2014
The acquisition of resistance towards FAS-mediated apoptosis may be required for tumor formation. Tumors from various histological origins exhibit FAS mutations, the most frequent being hematological malignancies. However, data regarding FAS mutations or FAS signaling alterations are still lacking in precursor T-cell lymphoblastic lymphomas (T-LBLs ...
Villa-Morales, M, Cobos, M A, González-Gugel, E, Álvarez-Iglesias, V, Martinez-Delgado, Beatriz, Piris, M A, Carracedo, A, Benitez, Javier, Fernández-Piqueras, J   +8 more
openaire   +5 more sources

Blastic transformation of mantle cell lymphoma with B-lymphoblastic features

Human Pathology: Case Reports, 2019
Mantle cell lymphoma is characterized by the presence of the t(11;14)(q13;q32), which is found in more than 95% of cases. We present a case of mantle cell lymphoma with the typical phenotype, which transformed to a blastic morphology with loss of ...
David Cantu, Yuridia Alvarado, Joyce Murata-Collins, Dennis D. Weisenburger   +3 more
doaj   +1 more source

Adult T-type lymphoblastic lymphoma presenting as hypercalcemic crisis and aplastic anemia: a case report

Journal of Medical Case Reports, 2019
Background Hypercalcemia and aplastic anemia are two uncommon presentations of non-Hodgkin lymphoma that potentially worsen the disease prognosis. Although hypercalcemia has been reported in the B-cell subtypes and some T-cell subtypes of non-Hodgkin ...
Mickael Essouma, Dorothée M. Soh, Mazou N. Temgoua, Ronald M. Gobina, Aristide T. Nono, Etienne Olivier Atenguena, Mahamat Maimouna, Gloria E. Ashuntantang   +7 more
doaj   +1 more source

Immunohistochemical (IHC) Analysis of Non-Hodgkin’s Lymphoma (NHL) Spectrum According to WHO/REAL Classification: A Single Centre Experience from Punjab, India [PDF]

Journal of Clinical and Diagnostic Research, 2014
Introduction: The distribution of the major subtypes of non-Hodgkin’s lymphoma (NHL) differs across geographic regions. This study, from the north Indian state of Punjab, has incorporated immunophenotypic findings while investigating the distribution
Manisha Sharma, Rahul Mannan, Mohit Madhukar, Sanjay Navani, Mridu Manjari, Tejinder Singh Bhasin, Karamjit Singh Gill   +6 more
doaj   +1 more source

Lineage switch from lymphoma to myeloid neoplasms: First case series from a single institution

Open Medicine, 2022
Lymphoma relapse is very common in clinical work, but lineage switch at relapse is rare. Although some cases have reported acute lymphocytic leukemia (ALL) switch to acute myeloid leukemia (AML) or myeloid sarcoma upon relapse, phenotype switch seldom ...
Yang Wenjuan, Xie Shuangfeng, Li Yiqing, Wang Jieyu, Xiao Jie, Huang Kezhi, Wang Xiuju, Wu Yudan, Ma Liping, Nie Danian   +9 more
doaj   +1 more source

Orbital T‐cell lymphoblastic lymphoma

Acta Ophthalmologica, 2015
PurposeTo present the clinical, pathological and genetic characteristics of a case of primary T‐cell lymphoblastic lymphoma of the orbit.MethodsClinical work‐up and morphological – and immunohistochemical study. Genetic analyses using FISH, DNA sequencing and arrayCGH analysis.ResultsA 22‐year‐old man presented with a 3‐week period of headache, reduced
S. Heegaard, L. Stenman
openaire   +1 more source

γδ TCR T lymphoblastic leukemia in a child presenting with marked hyperleukocytosis

Clinical Case Reports, 2021
γδ TCR T lymphoblastic leukemia is rare in children and should be differentiated mainly from hepatosplenic T‐cell lymphoma in this age group.
Jirong Mass, Bachir Alobeid
doaj   +1 more source