Results 1 to 10 of about 33,050 (136)

Precursor T-Cell acute lymphoblastic leukemia/lymphoma with rare presentation in the urinary bladder [PDF]

open access: yesHematology Reports, 2011
We present the 16th reported case of Acute Lymphoblastic Leukemia (ALL) with involvement in the bladder. Our patient was a 22 yearold man with T-cell ALL with a mediastinal mass.
Alexander Pham   +5 more
doaj   +5 more sources

Haploidentical CD7 CAR T-cells induced remission in a patient with TP53 mutated relapsed and refractory early T-cell precursor lymphoblastic leukemia/lymphoma [PDF]

open access: yesBiomarker Research, 2022
Patients with relapsed/refractory early T-cell precursor lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) respond poorly to traditional therapy and have dismal prognosis.
Hai-ping Dai   +9 more
doaj   +4 more sources

An unusual presentation of precursor T cell lymphoblastic leukemia/lymphoma with cholestatic jaundice: case report [PDF]

open access: yesJournal of Hematology & Oncology, 2009
Background Cholestatic jaundice as a presenting symptom of Precursor T-lymphoblastic leukemia (T-ALL)/lymphoma (T-LBL) has never been reported in literature. Similarly, precursor T-ALL/T-LBL is characteristically negative for synaptophysin. We report the
Latif Sahibzada U   +2 more
doaj   +3 more sources

Safety and efficacy of bispecific antibodies in hematologic neoplasms: a systematic review [PDF]

open access: yesFrontiers in Immunology
BackgroundHematologic neoplasms remain a growing global burden, with relapse, resistance, and limited treatment options persisting. Bispecific antibodies (BsAbs) offer a novel multi-antigen targeting strategy.
Khanittha Lommuang   +1 more
doaj   +2 more sources

Isolated Central Nervous System Presentation of Early T-Cell Precursor Acute Lymphoblastic Leukemia/Lymphoma: A Rare Case of Exclusive Brain Involvement

open access: yesCase Reports in Hematology
Early T-cell precursor acute lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) is a high-risk and biologically distinct subset of T-cell acute lymphoblastic leukemia, typically characterized by leukemic involvement of bone marrow, peripheral blood, and ...
Violet O. Swart, Behyar Zoghi
doaj   +3 more sources

CBFA2T3::GLIS2‐positive acute leukemia with RAM and mixed T/megakaryocytic phenotype

open access: yeseJHaem, 2023
Herein, we present a rare case of acute myeloid leukemia (AML) with CBFA2T3‐rearrangement and the expression of megakaryocytic and lymphoid markers, highlighting the need for a high suspicion index in differential diagnosis and applying adequate workup ...
Mahsa Khanlari   +8 more
doaj   +1 more source

Development‐dependent expression of cyclin D3 in precursor T‐cell lymphoblastic leukemia/lymphoma [PDF]

open access: yesPathology International, 2007
In contrast to the clear oncogenic role of cyclins D1 and D2, cyclin D3 is suggested to have a role in the initiation and/or maintenance of differentiation in a lineage‐associated manner in addition to its basic role in proliferation. Recently, it has been reported that in cyclin D3‐deficient mice, normal expansion of T lymphocytes is impaired because ...
Eiichi, Sasaki   +7 more
openaire   +2 more sources

Inclusion of the Inducible Caspase 9 Suicide Gene in CAR Construct Increases Safety of CAR.CD19 T Cell Therapy in B-Cell Malignancies

open access: yesFrontiers in Immunology, 2021
T cells engineered with chimeric antigen receptor (CAR-T cells) are an effective treatment in patients with relapsed/refractory B-cell precursor acute lymphoblastic leukemia or B-cell non-Hodgkin lymphoma.
Marika Guercio   +20 more
doaj   +1 more source

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