Results 11 to 20 of about 14,826,476 (192)

Flow Cytometry-Guided Diagnosis of Cortical T-Lymphoblastic Lymphoma Presenting With a Massive Mediastinal Mass and Borderline Bone Marrow Involvement. [PDF]

J Clin Lab Anal
ABSTRACT Background T‐cell lymphoblastic lymphoma (T‐LBL) and T‐cell acute lymphoblastic leukemia (T‐ALL) are considered a single biological entity, distinguished primarily by the extent of bone marrow infiltration. This distinction becomes diagnostically challenging in patients with borderline marrow blast counts and predominantly extramedullary ...
Glait-Santar C, Moshe Y, Ayelet IA, Katz BZ.   +3 more
europepmc   +2 more sources

Bortezomib-based chemotherapy in Chinese pediatric patients with relapsed/refractory acute lymphoblastic leukemia: A single-center retrospective study. [PDF]

Pediatr Investig
Bortezomib‐based chemotherapy achieved an 88.9% remission rate in Chinese pediatric patients with relapsed/refractory B‐cell acute lymphoblastic leukemia, enabling 62.5% of responders to bridge to transplantation, while T‐cell acute lymphoblastic leukemia showed no response.
Zhao X, Wang J, Que L, Zhou D, Fang J, Xu L.   +5 more
europepmc   +2 more sources

Allogeneic Hematopoietic Stem Cell Transplantation Achieves Durable Remission in Blast-Phase Chronic Myeloid Leukemia Presenting as Early T-Cell Precursor Acute Lymphoblastic Leukemia. [PDF]

EJHaem
ABSTRACT Introduction The presentation of chronic myeloid leukemia (CML) in the blast phase as early T‐cell precursor acute lymphoblastic leukemia (ETP‐ALL) is very rare. As previously reported, in contrast to B‐ALL, the prognosis is poor. Case Presentation We encountered a patient with blast phase CML presenting as ETP‐ALL.
Tsushima T, Konishi Y, Yoda N, Wada K, Okamoto K, Matsuo K, Isogai S, Shimoji S, Utsu Y, Masuda SI, Aotsuka N.   +10 more
europepmc   +2 more sources

Expressió de ZAP-70 en linfòcits B normals i síndromes limfoproliferatives B [PDF]

, 2006
[cat] La Leucèmia Limfàtica Crònica (LLC), la més freqüent de les leucèmies en el món occidental, és una malaltia produïda per la proliferació i cúmul de limfòcits B madurs, actualment incurable.
Crespo Maull, Marta
core   +6 more sources

Gene expression profiling of precursor T-cell lymphoblastic leukemia/lymphoma identifies oncogenic pathways that are potential therapeutic targets [PDF]

Leukemia, 2007
We compared the gene expression pattern of thymic tumors from precursor T-cell lymphoblastic lymphoma/leukemia (pre-T LBL) that arose in transgenic mice that overexpressed SCL, LMO1 or NUP98-HOXD13 (NHD13) with that of thymocytes from normal littermates.
Y-W, Lin, P D, Aplan
openaire   +2 more sources

The Clinical Characteristics and Prognosis of AYA and Older Adult ETP-ALL/LBL: A Real-World Multicenter Study in China

Frontiers in Oncology, 2022
Early T-cell precursor (ETP) lymphoblastic leukemia/lymphoma is a high-risk T lymphoblastic leukemia/lymphoma (T-ALL/LBL) subgroup. We performed a real-world multicenter study to explore the clinical characteristics and prognosis of adolescent and young ...
Jinyan Xiao, Zihong Cai, Hao Wang, Xuekai Li, Biqi Zhou, Yujie Liu, Ying Wang, Peipei Xu, Peipei Xu, Li Wang, Li Wang, Depei Wu, Liping Dou, Liping Dou, Hongsheng Zhou, Hongsheng Zhou, Yang Xu, Yang Xu   +17 more
doaj   +1 more source

A Case of B-cell Precursor Acute Lymphoblastic Leukemia with the t(14;22)(q32;q11) Presenting Hyperleukocytosis

Clinical Pediatric Hematology-Oncology, 2022
B-cell precursor acute lymphoblastic leukemia (BCP-ALL), which is the most common type of ALL, has an excellent prognosis with long-term event-free survival of 90%.
Jianne Lee, Sun Young Kim, Yeon Jung Lim
doaj   +1 more source

DETECTION OF HEMATOPOIETIC NEOPLASMS IN CEREBROSPINAL FLUID BY IMMUNOPHENOTYPING: SINGLE-CENTER DATA ANALYSIS

Hematology, Transfusion and Cell Therapy, 2021
Introduction: Cerebrospinal fluid (CSF) infiltration can be identified at diagnosis and during the course of many hematopoietic malignancies, mainly acute leukemia and aggressive non-Hodgking lymphomas (NHL).
GF Bevilacqua, CM Bertolucci, AR Severino, RL Teotonio, M Penitenti, JE Conti-Spilari, MRV Ikoma-Colturato   +6 more
doaj   +1 more source

Outcome of Patients with T-Cell Acute Lymphoblastic Leukemia/Lymphoma with Early T-Cell Precursor-like Immunophenotype with Strong CD5 Expression

Blood, 2020
Introduction: T-cell acute lymphoblastic leukemia (T-ALL) originating from early T-cell precursors (ETP-ALL) has distinct immunophenotype (CD1a-CD8-CD5-/weak and positive for myeloid or stem-cell markers [My-HSC+]) and is associated with poor outcome with 5-year (yr) survival <25%. Some T-ALL cases are transcriptionally similar to
Kiyomi Morita, Hagop M. Kantarjian, Hong Fang, Farhad Ravandi, Nitin Jain, Marina Konopleva, El Hussein Siba, Feng Wang, Nicholas J. Short, Koichi Takahashi, Rita Khouri, Koji Sasaki, Courtney D. DiNardo, Tapan M. Kadia, Guillermo Garcia-Manero, Naval Daver, Guillermo Montalban Bravo, Sergej Konoplev, Joseph D. Khoury, Elias Jabbour   +19 more
openaire   +1 more source

Early T-cell precursor acute lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) in adolescents and adults: a high-risk subtype [PDF]

Blood, 2016
Key Points Adult patients with ETP-ALL/LBL have poor long-term outcomes. Novel therapies are urgently needed for adult patients with ETP-ALL/LBL.
Nitin, Jain, Audrey V, Lamb, Susan, O'Brien, Farhad, Ravandi, Marina, Konopleva, Elias, Jabbour, Zhuang, Zuo, Jeffrey, Jorgensen, Pei, Lin, Sherry, Pierce, Deborah, Thomas, Michael, Rytting, Gautam, Borthakur, Tapan, Kadia, Jorge, Cortes, Hagop M, Kantarjian, Joseph D, Khoury   +16 more
openaire   +2 more sources