Results 201 to 210 of about 568,663 (342)

A rare case of hepatosplenic gamma‐delta T‐cell lymphoma and secondary hemophagocytic lymphohistiocytosis [PDF]

, 2018
Philip Brandt, Leena T. Rahmat, Syed Sohail Ali   +2 more
openalex   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

TOPK Inhibition Promotes Anti‐Tumor Immunity Via eIF4F Complex Mediated STAT1 Translation in Gastric Cancer

Advanced Science, EarlyView.
This study identifies TOPK as a dual‐function target in gastric cancer: it drives tumor cell proliferation and migration, and under IFN‐γ stimulation, phosphorylates eIF4F complex component eIF4A1 to enhance STAT1 mRNA translation, thereby promoting PD‐L1/IDO1‐mediated tumor immunometabolic evasion.
Junbing Chen, Longtao Huangfu, Gangjian Wang, Xueying Wang, Huanbo Zhu, Qian Yao, Cong Chen, Xiaohuan Tang, Ting Guo, Biao Fan, Xingyang Liu, Qingda Li, Zining Liu, Ying Hu, Tianze Sun, Jiafu Ji, Xiaofang Xing   +16 more
wiley   +1 more source

Radiotherapy in addition to systemic therapy reduces the early mortality of angioimmunoblastic T-cell lymphoma. [PDF]

Ann Hematol
Lin Y, Lin Q, Xu Q, Shi S, Huang D, Ju G, Liu S, Song J, Lin Q, Chen J.   +9 more
europepmc   +1 more source

A Modular DNAzyme for Precise Visualization and Intervention of Alternative Splicing Isoforms in Live Cells

Advanced Science, EarlyView.
A Stringent dUPlex‐activated Error Robust (SUPER) DNAzyme system enables real‐time imaging of alternative mRNA splicing (e.g., Bcl‐xL/Bcl‐xS) in living cells via target‐triggered split‐DNAzyme reassembly and dual‐color fluorescence. It also achieves mRNA‐selective knockdown through DNAzyme‐based gene regulation, serving as a versatile tool for splicing
Mengru Lin, Jiale Sun, Yuqing Mao, Yuhao Tang, Fuan Wang, Zhihong Liu, Jing Wang   +6 more
wiley   +1 more source

TRBC1/TRBC2 Immunophenotyping Provides Added Value During the Diagnostic Workup of T-Cell Lymphoma. [PDF]

EJHaem
Taylor J, Lakum T, Bevan S, Freeman T, Boot J, Bigogno CM, Raine J, Hookway E, Medani H, Calaminici M, Okosun J, Grantham M, Araf S, Smith M, Butler T, Farren T.   +15 more
europepmc   +1 more source

T-cell rich B-cell large cell lymphoma.

, 1991
Soji Kurita, Shigeo Nakamura, Takashi Koshikawa, Kiyoko FUSE, Keiko Nakazato, Etsuko Kato, Sadayuki Kaba, Katsuko OKUDA, Taizan Suchi   +8 more
openalex   +2 more sources

Unexpected finding of T-cell lymphoma in a previously healthy 16-year-old patient after a thorax trauma: a case report [PDF]

, 2014
Anna Bach Okholm-Hansen, Stig Brorson
openalex   +1 more source

Dynamic Decoration of DNA Scaffolds for High‐Resolution Cancer Cell Subtyping

Advanced Science, EarlyView.
This study presents a dual‐mode imaging platform that utilizes self‐assembly and disassembly of DNA scaffolds for high‐resolution cancer cell detection. The structural rigidity of DNA scaffolds effectively prevents cellular internalization for over 300 min.
Xiaolin Hu, Jie Xie, Xinlin Guo, Liangting Wang, Zhengheng Yu, Xiaopei Qiu, Heng Li, Kang Wang, Xiaoxing Wang, Mingxuan Song, Junsong Guo, Wei Gu, Sergio Bernardini, Chaoyong Yang, Hong Zhang, Yang Luo   +15 more
wiley   +1 more source

Pioneering the future: nanotechnology's role in angioimmunoblastic T-cell lymphoma. [PDF]

Ann Med Surg (Lond)
Anjum HM, Ahmad J, Talha M, Shamim L, Imran SB.   +4 more
europepmc   +1 more source