Results 241 to 250 of about 568,663 (342)

Nasal T-cell Lymphoma

open access: yesInternal Medicine, 2006
Isao, Miyoshi   +6 more
openaire   +3 more sources

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

Primary Cutaneous Peripheral T-Cell Lymphoma With Follicular Helper T-Cell Phenotype. [PDF]

open access: yesJ Cutan Pathol
Planella-Fontanillas N   +9 more
europepmc   +1 more source

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

open access: yesAdvanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen   +15 more
wiley   +1 more source

A case of extranodal NK/T cell lymphoma, nasal type arising bilaterally in a necrotizing ulcer of the maxilla.

open access: bronze, 2002
Koichiro Tateishi   +5 more
openalex   +2 more sources

Dual Aptamers‐Based SETDB1 PROTACs as Effective Anti‐Tumor Strategies for Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study establishes dual‐aptamer PROTACs targeting SETDB1 using a SETDB1‐specific aptamer conjugated to AS1411. The designed PROTACs penetrate cells, recruit MDM2 to degrade SETDB1, and inhibit cancer cell proliferation and migration. Remarkably, they also overcome tamoxifen resistance and enhance CD8+ T cell cytotoxicity, suppressing tumor growth ...
Yanxuan Guo   +6 more
wiley   +1 more source

Primary central nervous system T-cell lymphoma: a single-centre retrospective study and literature review. [PDF]

open access: yesBMJ Neurol Open
Chen Y   +9 more
europepmc   +1 more source

A Case of CD30-Positive Adult T-Cell Leukemia/Lymphoma Presenting Spontaneous Regression and Recurrence of Skin Lesions

open access: diamond, 2014
Yumiko Kaku   +6 more
openalex   +1 more source

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