Results 171 to 180 of about 164,918 (277)

Bronchus-associated lymphoid tissue: a review of its development and function, including recent findings on the impact of environmental particulate exposure. [PDF]

Clin Exp Med
Mikami Y, Kuroda E, Kimura S, Hayatsu M, Watanabe K, Tsuda H, Nakamura Y, Sagawa T, Ichinose T, Takano H, Toriumi T.   +10 more
europepmc   +1 more source

Substance P recognition by a subset of human T lymphocytes.

Journal of Clinical Investigation, 1984
D. Payan, D. Brewster, A. Missirian-Bastian, E. Goetzl   +3 more
semanticscholar   +1 more source

TMEM131‐Mediated Soluble TRAIL Triggered Type II Alveolar Epithelial Cell Senescence in Radiation‐Induced Lung Injury

Advanced Science, EarlyView.
TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han, Chunsheng Wang, Xiuli Guo, Yuan Luo, Jianguo Zhang, Fajian He, Zihang Zeng, Jiang Luo, Wen Ouyang, Yan Gong, Conghua Xie   +10 more
wiley   +1 more source

A multi-epitope vaccine targeting a key virulence factor ClfA: An In-silico approach to combat Staphylococcus aureus infections. [PDF]

PLoS One
Nirob MNH, Sultana I, Al Arian T, Islam MS, Moniruzzzaman M, Nosi SJ, Halder SK, Shil A, Himel MK.   +8 more
europepmc   +1 more source

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

Increased Tph cells are associated with disease activity and elevated plasma TGF-β1 levels in systemic lupus erythematosus. [PDF]

Medicine (Baltimore)
Wu C, Su Y, Lan S, Liu J, Ding J, Wu H, Dai Y, Gao F, Yan Q.   +8 more
europepmc   +1 more source

PLA2G16‐Mediated Tetracosatetraenoic Acid Rewires Fatty Acid Oxidation to Impair CD8+ T Cell Immune Function in Promoting Breast Cancer Lung Metastasis

Advanced Science, EarlyView.
Illustrating how tumor‐derived PLA2G16 regulates tetracosatetraenoic acid (C24:4 (n‐6)) accumulation and CD8+ T cell activation via the C24:4‐PPARα‐FAO axis in early metastatic niches, thereby promoting lung metastasis of triple‐negative breast cancer.
Yubi Gan, Die Meng, Lei Lang, Jing Luo, Peijin Dai, Chao Chang, Zexiu Lu, Yuetong Guo, Rui Wang, Shanchun Chen, Xi Tang, Yixuan Hou, Dongmei Tan, Manran Liu   +13 more
wiley   +1 more source

Critical Evaluation of the Role of Transcription Factor RAR-Orphan Receptor-γt in the Development of Chronic Inflammatory Dermatological Diseases: A Promising Therapeutic Target. [PDF]

Biomolecules
Pramanik A, Mondal P, Bhattacharyya S.
europepmc   +1 more source

Safety and Efficacy of Adoptive Transfer of Stem Cell Memory Enriched Virus Specific T Cells against CMV and EBV

Advanced Science, EarlyView.
This study finds that CD8⁺ TSCM cells exhibit superior self‐renewal, differentiation, and antiviral activity. Transcriptome and epigenome analyses highlight MAPK cascade regulation in TSCM cells. In vivo, virus‐specific TSCM cells show enhanced persistence and tumor protection.
Xun‐Hong Cao, Xu‐Ying Pei, Yuan‐Yuan Zhang, Juan Xie, Jing‐Wei Tu, Zhuo‐Jun Liu, Yi‐Yang Ding, Chen‐Hua Yan, Yu‐Hong Chen, Yu Wang, Lan‐Ping Xu, Xiao‐Hui Zhang, Xiao‐Jun Huang, Xiang‐Yu Zhao   +13 more
wiley   +1 more source

Baseline Dysregulation in B, T, and NK Cells in COVID-19 Predicts Increased Late Mortality but Not Long-COVID Symptoms: Results from a Single-Center Observational Study. [PDF]

Viruses
Matyja-Bednarczyk A, Dziedzic R, Drynda A, Gradzikiewicz A, Bociąga-Jasik M, Wójcik K, Lichołai S, Górka K, Celejewska-Wójcik N, Stachura T, Polok K, Zaręba L, Iwaniec T, Sładek K, Bazan-Socha S.   +14 more
europepmc   +1 more source