Immune alterations in vestibular neuritis: a retrospective database pilot study on T and B lymphocyte profiles and cytokine levels [PDF]
BackgroundVestibular neuritis (VN) etiology remains elusive, with hypotheses suggesting viral infection, non-infectious inflammation, or immune responses.
Zhaohui Song +8 more
doaj +2 more sources
Heterogeneity of helper/inducer T lymphocytes. I. Lymphokine production and lymphokine responsiveness. [PDF]
Antigen-specific, Ia-restricted helper/inducer T lymphocytes consist of subsets that can be distinguished by lymphokine secretion. One, called Th1, secretes IL-2 and the other, termed Th2, produces BSF-1/IL-4 in response to stimulation by lectin or antigen receptor signals, and each uses the respective lymphokine as its autocrine growth factor.
E A, Kurt-Jones +4 more
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Clearance of Giardia muris infection requires helper/inducer T lymphocytes. [PDF]
The aim of this work was to identify the T cell subset (helper/inducer or cytotoxic/suppressor) that plays a major part in the clearance of Giardia muris infection. BALB/c mice were selectively depleted of helper/inducer (Th/i) or cytotoxic/suppressor (Tc/s) T cells, by treatment with rat IgG monoclonal antibodies directed against the Th/i cell surface
M F, Heyworth, J R, Carlson, T H, Ermak
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Transfusions enriched for W3/25+ helper/inducer T lymphocytes prevent spontaneous diabetes in the BB/W rat [PDF]
Transfusions of spleen cells are known to prevent spontaneous autoimmune diabetes in susceptible BB/W rats, while T cell-depleted transfusions are ineffective. To characterize further the protective cell(s), we transfused young diabetes prone rats with splenocytes from diabetes resistant BB/W rats that were treated in vitro to enrich them in either OX8+
J P, Mordes +6 more
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Heterogeneity of helper/inducer T lymphocytes. II. Effects of interleukin 4- and interleukin 2-producing T cell clones on resting B lymphocytes. [PDF]
To compare the helper function of murine T cell clones that secrete IL-2 and IFN-gamma (Th1 cells) or IL-4 and IL-5 (Th2), purified resting B cells were stimulated with F(ab')2 rabbit anti-mouse Ig (RAMG) and rabbit Ig-specific, class II MHC-restricted cloned T cells belonging to the two subsets.
Boom, WH, Liano, D, Abbas, AK
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Innate lymphoid cells (ILCs) were firstly described by different independent laboratories in 2008 as tissue-resident innate lymphocytes mirroring the phenotype and function of T helper cells. ILCs have been subdivided into three distinct subgroups, ILC1,
Michela Calvi +8 more
doaj +1 more source
Immunological alterations in patients with primary tumors in central nervous system [PDF]
Natural killer (NK) cells play an important role in immune surveillance against tumors. The present work aimed to study the cytotoxic activity of NK cells and T cell subsets in peripheral blood of 13 patients with primary tumors in central nervous system
MARIA TEREZINHA S. PERAÇOLI +10 more
doaj +1 more source
ASSESSMENT OF THE PERCENTAGES OF T-LYMPHOCYTE SUBSETS IN THE PERIPHERAL BLOOD OF MEDITERRANEAN SPOTTED FEVER PATIENTS [PDF]
PURPOSE: Mediterranean spotted fever (MSF) is a rickettsial disease. THE AIM was to evaluate the host immunе response to Rickettsia conorii. MATERIAL AND METHODS: 62 patients were assigned into three groups: with mild, moderate or severe clinical forms ...
Iv. Baltadzhiev, P. Pavlov
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Helper-Inducer T-Lymphocytes Mediate Diabetes in EMC-Infected BALB/c By J Mice [PDF]
Diabetes mellitus developing in BALB/c ByJ mice infected with the M variant of encephalomyocarditis (EMC) virus is dependent on thymic immune mechanisms. We treated mice with the anti-Tlymphocyte monoclonal anti-L3T4 and anti-Lyt2.2 antibodies before virus inoculation and monitored the infection and occurrence of diabetes thereafter.
M K, Haynes, S A, Huber, J E, Craighead
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The aim of the study is to conduct a comparative analysis of percentages for peripheral blood effector lymphocyte subsets in patients with uveal melanoma manifested by recurrent and chronic herpesvirus infection.
N. V. Balatskaya +4 more
doaj +1 more source

