Results 231 to 240 of about 164,918 (277)

Role of cDC2 in priming CD8⁺ T cells in cancer. [PDF]

J Immunother Cancer
Hamouda AEI, Laoui D.
europepmc   +1 more source

Pre‐Existing Th1 Immunity Outperforms Age in Predicting Antibody Responses to SARS‐CoV‐2 Inactivated Vaccines

Advanced Science, EarlyView.
Challenging the focus on age, this study finds pre‐existing T helper 1 cells are the key biomarker for predicting antibody response to SARS‐CoV‐2 inactivated vaccines. In both mice and humans, high responders exhibited elevated baseline T helper 1 cells, which correlated with robust humoral immunity, offering crucial guidance for improving vaccine ...
Chanyuan Ye, Xiaoli Zhang, Lingfeng Qiu, Jia Ji, Jueqing Gu, Hongyu Jia, Yingfeng Lu, Jiyang Chen, Zelu Meng, Jiangshan Lian, Hangping Yao, Xun Zeng, Yida Yang   +12 more
wiley   +1 more source

Mesenchymal stromal cells attenuate primary sjogren's syndrome by modulating PD-1⁺CXCR5^- T peripheral helper cells via galectin-1. [PDF]

Stem Cell Res Ther
Zhang S, Yin F, Chai R, Li T, Gao Y, Chen X, Yao G, Tang X, Han X, Tsao BP, Geng L, Sun L.   +11 more
europepmc   +1 more source

Mutual Exclusion Analysis Shows that DUSP9 Negatively Regulates PD‐L1 Expression and Acts as a Target to Enhance Anti‐PD‐1 Efficacy

Advanced Science, EarlyView.
A mutually exclusive screening system is established to identify negative regulators of highly plastic genes. Dual specificity phosphatase (DUSP9) is a novel negative regulatory molecule of PD‐L1 by dephosphorylating STAT3, and acts as a target molecule in combination with PD‐1 antibody for tumor immunotherapy and a new clinical biomarker for ...
Yuzhe Hu, Ling Tang, Zheng Kuang, Danyi Huang, Ting Li, Gaofei Yin, Yingyu Chen, Wei Guo, Wenling Han, Pingzhang Wang   +9 more
wiley   +1 more source

Inhibition of estrogen receptor alpha stabilizes regulatory T cell function in autoimmune hepatitis. [PDF]

JHEP Rep
Zhang L, Gromova B, Nguyen DH, Cagle C, Gomes GS, Li W, Gao L, Zhang W, Graham JJ, Wang N, Kalbasi A, Csizmadia E, Wei A, Cassavaugh J, Bonder A, Patwardhan V, Jiang S, Kota SK, Longhi MS.   +18 more
europepmc   +1 more source

Hepatitis C virus modified _SE2_F442NYT-mRNA-LNP candidate vaccine promotes helper CXCR5⁺T cells. [PDF]

J Virol
Haga Y, Babu E P, Swiderska-Syn M, Reagan EK, Weissman D, Ray R.   +5 more
europepmc   +1 more source

Variation in Immune and Inflammatory Blood Markers in Advanced Melanoma Patients Treated with PD-1 Inhibitors: A Preliminary Exploratory Study. [PDF]

Biomedicines
Bolovan LM, Panait ME, Busca A, Stanciu AE, Chiriac D, Mihalcea CE, Hotnog CM, Georgescu MT, Voinea SC, Prunoiu VM, Brasoveanu LI, Gales LN.   +11 more
europepmc   +1 more source

Augmented MHC Class I on Professional Antigen-Presenting Cells and Enhanced Cytokine Production by CD8⁺ T Cells in Type 2 Diabetes Mellitus. [PDF]

Eur J Immunol
Liu S, Jayasinghe T, Kamińska D, Xu X, Ren X, Jiao Y, Kong Y, Li X, Li K, Antoniou AN, Li W, Błażewska K, Gendaszewska-Darmach E, Xu J, Garstka MA.   +14 more
europepmc   +1 more source

Case Report: Severe <i>Pneumocystis jirovecii</i> pneumonia following zuberitamab treatment in autoimmune hemolytic anemia. [PDF]

Front Immunol
Yang Q, Ding P, Liu YX, Zhang KC, Gao PY.   +4 more
europepmc   +1 more source

Impaired humoral and T helper cell responses to toxic shock syndrome toxin-1 (TSST-1) in granulomatosis with polyangiitis. [PDF]

Rheumatology (Oxford)
Liao H, Rutgers A, Huitema MG, Roozendaal C, Heeringa P, Abdulahad WH.   +5 more
europepmc   +1 more source