Structural modification of clofoctol yielded a novel blood‐brain barrier‐permeable compound, B7, featuring a multi‐substituted diaryl scaffold. B7 demonstrates potent anti‐glioblastoma activity by suppressing glioblastoma stem cells proliferation, migration, and invasion through interactions with five key residues of poliovirus receptor cell adhesion ...
Yong‐jian Wang+9 more
wiley +1 more source
Activation-induced cytidine deaminase in tertiary lymphoid structures: dual roles and implications in cancer prognosis. [PDF]
Lv Z+5 more
europepmc +1 more source
CXCL13 Expression Promotes CAR T Cell Antitumor Activity and Potentiates Response to PD‐1 Blockade
This study demonstrates that engineering CAR T cells to express CXCL13 enhances their antitumor efficacy and significantly improves responsiveness to PD‐1 immune checkpoint blockade. CXCL13 promotes T cell persistence, and resistance to early exhaustion via the AKT‐mTOR pathway.
Yang Zhou+15 more
wiley +1 more source
Elevated Proportions of Circulating CXCR5+ Follicular Helper T Cells Reflect the Presence of Airway Obstruction in Asthma. [PDF]
Tsukuda TK+6 more
europepmc +1 more source
Immunomodulatory interactions between mesenchymal stromal/stem cells and immune cells in psoriasis: therapeutic potential and challenges. [PDF]
Dashti M+3 more
europepmc +1 more source
Real-World Data on the p.Gly17Val RHOA Mutation in Diagnosing T Follicular Helper Cell Lymphomas. [PDF]
Tsuboi Y+15 more
europepmc +1 more source
<i>In Silico</i> Driven Multi-Epitope Subunit Candidate Vaccine against Bovine Tuberculosis. [PDF]
Faysal MA+7 more
europepmc +1 more source
Follicular helper- and peripheral helper-like T cells drive autoimmune disease in human immune system mice. [PDF]
Khosravi-Maharlooei M+11 more
europepmc +1 more source