This study utilized Ss‐STARR‐seq to construct a genome‐wide silencer map of mouse cells and elucidated the fundamental characteristics of these silencers. These silencers exist in a cell‐specific manner and exhibit unique epigenetic modifications. Through functional experiments, we also discovered that these silencers can regulate gene expression and ...
Xiusheng Zhu+12 more
wiley +1 more source
T and B lymphocyte antigen-positive null cell leukemias [PDF]
Joseph Kaplan+2 more
openalex +1 more source
Global Trends in Research of Amino Acid Metabolism in T Lymphocytes in Recent 15 Years: A Bibliometric Analysis. [PDF]
Xu J, Yu Y, Li S, Qiu F.
europepmc +1 more source
Advances in Nano‐Immunomodulatory Systems for the Treatment of Acute Kidney Injury
Based on the biodegradability and the immunological reactiveness, IMNs can be broadly classified into four categories. The first category includes types of biologically derived materials that cause immunomodulatory action and biodegradability like nanoparticles of cell membranes, extracellular vesicles, and exosomes.
Chenli Zhang+5 more
wiley +1 more source
Alternative pathways of T lymphocyte activation. [PDF]
Fritz H. Bach, Benedict J. Alter
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Mcm5 mutation leads to silencing of Stat1-bcl2 which accelerating apoptosis of immature T lymphocytes with DNA damage. [PDF]
Liu M+13 more
europepmc +1 more source
Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu+7 more
wiley +1 more source
Cytotoxic Activity of Human Lymphocytes: Quantitative Analysis of T Cell and K Cell Cytotoxicity, Revealing Enzyme-Like Kinetics [PDF]
Wim P. Zeijlemaker+3 more
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Combined transcriptome and metabolome analysis of stable knockdown and overexpression of the CD8A gene in chicken T lymphocytes. [PDF]
Du Y+13 more
europepmc +1 more source
This study presents an innovative oral microalgae‐based biosystem to inhibit tumor growth, reduce PD‐1 expression, and activate immune responses of hepatocellular carcinoma. When combined with enhanced irreversible electroporation treatment, it demonstrates a synergistic effect that effectively reduces the tumor burden and enhances the tumor immune ...
Cheng Zeng+8 more
wiley +1 more source