Results 111 to 120 of about 121,594 (292)
Characterizations of Hyperrings by Fuzzy Hyperideals with Respect to A t-norm
Fuzzy Information and Engineering, 2017 In this paper, we inquire further into the properties on some kind fuzzy hyperideals and we study the hyperrings via T-fuzzy hyperideals. By means of the use of a triangular norm T, we define, characterize and study the T-fuzzy left and right hyperideals,
Kostaq Hila, Krisanthi Naka
doaj +1 more source
Various aggregation operators of the generalized hesitant fuzzy numbers based on Archimedean t-norm and t-conorm functions. [PDF]
Soft comput, 2022 Garg H, Keikha A.
europepmc +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Decision Making by Hybrid Probabilistic - Possibilistic Utility Theory [PDF]
It is presented an approach to decision theory based upon nonprobabilistic uncertainty. There is an axiomatization of the hybrid probabilisticpossibilistic mixtures based on a pair of triangular conorm and triangular norm satisfying restricted ...
Endre Pap
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Element-Oriented Construction Methods for Nullnorms on Bounded Lattices
AxiomsNullnorms are aggregation functions with an annihilator and are generalizations of t-norms and t-conorms. After the introduction of the concept of nullnorms on bounded lattices by Karaçal et al., the studies on their construction methods in such ...
Ümit Ertuğrul +2 more
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Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Probablistic convergence spaces and regularity
International Journal of Mathematics and Mathematical Sciences, 1997 The usual definition of regularity for convergence spaces can be characterized by a diagonal axiom R due to Cook and Fischer. The generalization of R to the realm of probabilistic convergence spaces depends on a t-norm T, and the resulting axiom RT ...
P. Brock, D. C. Kent
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source